open access

Vol 11, No 2 (2007)
Artykuły redakcyjne
Published online: 2007-05-18
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Arterial hypertension and type 1 diabetes mellitus

Paweł Uruski, Aleksandra Uruska, Dorota Zozulińska, Andrzej Tykarski
Nadciśnienie tętnicze 2007;11(2):85-94.

open access

Vol 11, No 2 (2007)
Artykuły redakcyjne
Published online: 2007-05-18

Abstract

Arterial hypertension in patients with type 1 diabetes, due to diagnosis and treatment, remains heavyweight clinical problem. In comparison with general population, hypertension in this group of patients, is more common and more malignant. It is connected with increased risk of macroangiopathy and microangiopathy, and cardiovascular deaths in young people. Pathogenesis of arterial hypertension in patients with type 1 diabetes, despite of the predominant role of diabetic nephropathy, is multifactorial and closely related to metabolic control of diabetes. Lack of big clinical trials considering this issue and unspecified guidelines of scientific associations, cause that treatment of hypertension in this group of patients has empirical character. Therefore at assortment of antihypertensive drugs in this patients we have to take under consideration, beside conclusions from studies on type 2 diabetes, also etiopathogenesis of the disease and usually young age of these patients and also particular conditionings (intensive insulinotherapy) and clinical situations typical for this group of patients e.g. higher risk of hypoglycaemia and possibility or plans of geting pregnant in young women. Antihypertensive drugs of first choice in DM 1 are ACEI, and ARB are only alternative in case of side effects. In medical care of patients with DM 1 and blood pressure disturbances cooperation between diabetologists and specialists in hypertension is necessary.

Abstract

Arterial hypertension in patients with type 1 diabetes, due to diagnosis and treatment, remains heavyweight clinical problem. In comparison with general population, hypertension in this group of patients, is more common and more malignant. It is connected with increased risk of macroangiopathy and microangiopathy, and cardiovascular deaths in young people. Pathogenesis of arterial hypertension in patients with type 1 diabetes, despite of the predominant role of diabetic nephropathy, is multifactorial and closely related to metabolic control of diabetes. Lack of big clinical trials considering this issue and unspecified guidelines of scientific associations, cause that treatment of hypertension in this group of patients has empirical character. Therefore at assortment of antihypertensive drugs in this patients we have to take under consideration, beside conclusions from studies on type 2 diabetes, also etiopathogenesis of the disease and usually young age of these patients and also particular conditionings (intensive insulinotherapy) and clinical situations typical for this group of patients e.g. higher risk of hypoglycaemia and possibility or plans of geting pregnant in young women. Antihypertensive drugs of first choice in DM 1 are ACEI, and ARB are only alternative in case of side effects. In medical care of patients with DM 1 and blood pressure disturbances cooperation between diabetologists and specialists in hypertension is necessary.
Get Citation

Keywords

arterial hypertension; diabetes mellitus type 1; pathophysiology; antihypertensive treatment

About this article
Title

Arterial hypertension and type 1 diabetes mellitus

Journal

Arterial Hypertension

Issue

Vol 11, No 2 (2007)

Pages

85-94

Published online

2007-05-18

Bibliographic record

Nadciśnienie tętnicze 2007;11(2):85-94.

Keywords

arterial hypertension
diabetes mellitus type 1
pathophysiology
antihypertensive treatment

Authors

Paweł Uruski
Aleksandra Uruska
Dorota Zozulińska
Andrzej Tykarski

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