open access

Vol 13, No 5 (2009)
Prace oryginalne
Published online: 2009-12-04
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Assessement of repeatability of aortic pulse wave velocity measurements

Paweł Stróżecki, Jacek Manitius
Nadciśnienie tętnicze 2009;13(5):327-335.

open access

Vol 13, No 5 (2009)
Prace oryginalne
Published online: 2009-12-04

Abstract


Background Pulse wave velocity (PWV) measurement is simple and non-invasive method to assess arterial stiffness, with prognostic value. The aim of the study was to assess PWV measurement repeatability.
Material nad methods The study population consists of 206 people, in whom one investigator performed two consecutive carotid-femoral PWV measurements, the first and immediately the second (PWV1, and PWV2, respectively). Measurement repatability was assessed using Bland and Altman method, by calculation correlation coefficient between results of the first and the second measurement, and by calculating intraclass correlation coefficient (ICC). For each pair of measurements the difference was calculated (D = PWV1 - PWV2), than mean D (Dśr.) and its standard deviation (SD) were calculated. The limits of agreement were determined as Dśr. ± 2SD.
Results For 92,7% pairs of measurement the difference was lower than limits of agreement, while according to British Standards Intitution 95% of differences to be less than two standard deviations. Statistically significant correlation was found between results of PWV1 and PWV2 in the study population: r = 0.89 (p < 0.00001), and ICC was 0.86. The size of the difference was correlated to blood pressure before first PWV measurement; the higher blood pressure, PWV2 was more lower than PWV1.
Conclusions Despite strong correlation between PWV measurements performed by one investigator, this method has no met criteria of high repeatibility. High blood pressure is one of the causes of difference between measurements.

Abstract


Background Pulse wave velocity (PWV) measurement is simple and non-invasive method to assess arterial stiffness, with prognostic value. The aim of the study was to assess PWV measurement repeatability.
Material nad methods The study population consists of 206 people, in whom one investigator performed two consecutive carotid-femoral PWV measurements, the first and immediately the second (PWV1, and PWV2, respectively). Measurement repatability was assessed using Bland and Altman method, by calculation correlation coefficient between results of the first and the second measurement, and by calculating intraclass correlation coefficient (ICC). For each pair of measurements the difference was calculated (D = PWV1 - PWV2), than mean D (Dśr.) and its standard deviation (SD) were calculated. The limits of agreement were determined as Dśr. ± 2SD.
Results For 92,7% pairs of measurement the difference was lower than limits of agreement, while according to British Standards Intitution 95% of differences to be less than two standard deviations. Statistically significant correlation was found between results of PWV1 and PWV2 in the study population: r = 0.89 (p < 0.00001), and ICC was 0.86. The size of the difference was correlated to blood pressure before first PWV measurement; the higher blood pressure, PWV2 was more lower than PWV1.
Conclusions Despite strong correlation between PWV measurements performed by one investigator, this method has no met criteria of high repeatibility. High blood pressure is one of the causes of difference between measurements.
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Keywords

arterial stiffness; hypertension; pulse wave velocity; repeatability of measurements

About this article
Title

Assessement of repeatability of aortic pulse wave velocity measurements

Journal

Arterial Hypertension

Issue

Vol 13, No 5 (2009)

Pages

327-335

Published online

2009-12-04

Bibliographic record

Nadciśnienie tętnicze 2009;13(5):327-335.

Keywords

arterial stiffness
hypertension
pulse wave velocity
repeatability of measurements

Authors

Paweł Stróżecki
Jacek Manitius

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