open access

Vol 51, No 1 (2019)
Review articles
Published online: 2019-03-21
Submitted: 2018-12-05
Accepted: 2019-02-19
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Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Jan Pluta, Janusz Trzebicki
DOI: 10.5603/AIT.2019.0011
·
Anaesthesiol Intensive Ther 2019;51(1):56-63.

open access

Vol 51, No 1 (2019)
Review articles
Published online: 2019-03-21
Submitted: 2018-12-05
Accepted: 2019-02-19

Abstract

Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.

Abstract

Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.
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Keywords

haemostasis, thrombocytes; thrombocytopenia; intensive care unit

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About this article
Title

Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 51, No 1 (2019)

Pages

56-63

Published online

2019-03-21

DOI

10.5603/AIT.2019.0011

Bibliographic record

Anaesthesiol Intensive Ther 2019;51(1):56-63.

Keywords

haemostasis
thrombocytes
thrombocytopenia
intensive care unit

Authors

Jan Pluta
Janusz Trzebicki

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