open access

Vol 50, No 2 (2018)
Letters to editor
Published online: 2018-06-26
Submitted: 2018-03-28
Accepted: 2018-05-25
Get Citation

Acquired haemophilia A imitating uterine tumour in a patient with de novo diagnosis of hepatitis C

Piotr Filip Czempik, Łukasz J. Krzych
DOI: 10.5603/AIT.2018.0021
·
Pubmed: 29953577
·
Anaesthesiol Intensive Ther 2018;50(2):170-172.

open access

Vol 50, No 2 (2018)
Letters to editor
Published online: 2018-06-26
Submitted: 2018-03-28
Accepted: 2018-05-25

Abstract

AHA is an extremely rare disorder, with annual incidence of 1.5 cases per million population. This clinical entity is caused by autoantibodies directed against coagulation factor VIII, what leads to decreased serum activity of thereof, and is characterized by spontaneous or induced by trauma, or invasive procedure bleeding. Approximately 50% of cases are idiopathic in origin, affecting both sexes, with median age at diagnosis of 74 years. We present a case report of a patient diagnosed with acquired haemophilia A (AHA) in the perioperative period.

Abstract

AHA is an extremely rare disorder, with annual incidence of 1.5 cases per million population. This clinical entity is caused by autoantibodies directed against coagulation factor VIII, what leads to decreased serum activity of thereof, and is characterized by spontaneous or induced by trauma, or invasive procedure bleeding. Approximately 50% of cases are idiopathic in origin, affecting both sexes, with median age at diagnosis of 74 years. We present a case report of a patient diagnosed with acquired haemophilia A (AHA) in the perioperative period.

Get Citation

Keywords

acquired haemophilia; bleeding; recombinant activated factor VII, activated prothrombin complex concentrate

About this article
Title

Acquired haemophilia A imitating uterine tumour in a patient with de novo diagnosis of hepatitis C

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 50, No 2 (2018)

Pages

170-172

Published online

2018-06-26

DOI

10.5603/AIT.2018.0021

Pubmed

29953577

Bibliographic record

Anaesthesiol Intensive Ther 2018;50(2):170-172.

Keywords

acquired haemophilia
bleeding
recombinant activated factor VII
activated prothrombin complex concentrate

Authors

Piotr Filip Czempik
Łukasz J. Krzych

References (7)
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  4. Kruse-Jarres R, Kempton CL, Baudo F, et al. Consensus recommendations for the diagnosis and treatment of acquired hemophilia A. BMC Res Notes. 2010; 3(7): 161–705.
  5. Green D, Lechner K. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost. 1981; 45(3): 200–203.
  6. Knoebl P, Marco P, Baudo F, et al. EACH2 Registry Contributors. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost. 2012; 10(4): 622–631.
  7. Kasper CK, Aledort L, Aronson D, et al. Proceedings: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh. 1975; 34(2): 612.

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