open access

Vol 48, No 3 (2016)
Original and clinical articles
Published online: 2016-05-20
Submitted: 2015-08-27
Accepted: 2016-03-09
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Hypoalbuminaemia at admission predicts the poor outcomes in critically ill children

Kulnipa Kittisakmontri, Sanit Reungrongrat, Mongkol Lao-araya
DOI: 10.5603/AIT.a2016.0028
·
Anaesthesiol Intensive Ther 2016;48(3):158-161.

open access

Vol 48, No 3 (2016)
Original and clinical articles
Published online: 2016-05-20
Submitted: 2015-08-27
Accepted: 2016-03-09

Abstract

BACKGROUND: Hypoalbuminaemia at admission is a common finding in patients admitted to the Paediatric Intensive Care Unit (PICU) and it is thought that this may predict morbidity and mortality.

METHODS: A retrospective study was conducted in the tertiary hospital. The medical records of critically ill children were reviewed. The data were analyzed for the prevalence of hypoalbuminaemia and outcomes.

RESULTS: Two hundred and two patients were included in the analysis. The incidence of hypoalbuminaemia at admission was 57.9%. These patients had a mortality rate 4 times greater (adjusted odds ratio 3.8; 95% CI: 1.4–10.0), a longer length of PICU stay (8.6 vs. 6.7 days, P = 0.04) and a longer period on a ventilator (5.9 vs. 3.9 days, P = 0.04) than patients with normal albumin levels.

CONCLUSIONS: Hypoalbuminaemia at admission was a predictive factor of poor outcome in critically ill children. It is associated with a higher mortality, a longer length of stay in the PICU, as well as longer ventilator use.

Abstract

BACKGROUND: Hypoalbuminaemia at admission is a common finding in patients admitted to the Paediatric Intensive Care Unit (PICU) and it is thought that this may predict morbidity and mortality.

METHODS: A retrospective study was conducted in the tertiary hospital. The medical records of critically ill children were reviewed. The data were analyzed for the prevalence of hypoalbuminaemia and outcomes.

RESULTS: Two hundred and two patients were included in the analysis. The incidence of hypoalbuminaemia at admission was 57.9%. These patients had a mortality rate 4 times greater (adjusted odds ratio 3.8; 95% CI: 1.4–10.0), a longer length of PICU stay (8.6 vs. 6.7 days, P = 0.04) and a longer period on a ventilator (5.9 vs. 3.9 days, P = 0.04) than patients with normal albumin levels.

CONCLUSIONS: Hypoalbuminaemia at admission was a predictive factor of poor outcome in critically ill children. It is associated with a higher mortality, a longer length of stay in the PICU, as well as longer ventilator use.

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Keywords

hypoalbuminaemia; prediction factor; clinical outcomes; critically ill children

About this article
Title

Hypoalbuminaemia at admission predicts the poor outcomes in critically ill children

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 48, No 3 (2016)

Pages

158-161

Published online

2016-05-20

DOI

10.5603/AIT.a2016.0028

Bibliographic record

Anaesthesiol Intensive Ther 2016;48(3):158-161.

Keywords

hypoalbuminaemia
prediction factor
clinical outcomes
critically ill children

Authors

Kulnipa Kittisakmontri
Sanit Reungrongrat
Mongkol Lao-araya

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