open access

Vol 47, No 4 (2015)
Original and clinical articles
Published online: 2015-07-26
Submitted: 2014-12-06
Accepted: 2015-04-02
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Epidemiology of new-onset paroxysmal atrial fibrillation in the General Intensive Care Unit population and after discharge from ICU. A retrospective epidemiological study

Leonid Koyfman, Evgeni Brotfain, Ruslan Kutz, Amit Frenkel, Andrei Schwartz, Avi Boniel, Alexander Zlotnik, Moti Klein
DOI: 10.5603/AIT.a2015.0040
·
Anaesthesiol Intensive Ther 2015;47(4):309-314.

open access

Vol 47, No 4 (2015)
Original and clinical articles
Published online: 2015-07-26
Submitted: 2014-12-06
Accepted: 2015-04-02

Abstract

BACKGROUND: Evidence of various cardiac arrhythmias in septic patients has been demonstrated by multiple clinical reports and observations. Most cardiac arrhythmias in sepsis are new-onset and may be related to sepsis-induced myocardial dysfunction. We propose to investigate and analyze data of new-onset paroxysmal atrial fibrillation (AF) in a critically ill septic population.

METHODS: This is a retrospective epidemiologic study. We collected clinical data from two hundred septic patients who developed a new episode of atrial fibrillation during their hospitalization in General Intensive Care Unit (GICU) between January 2007 and June 2013.

RESULTS: Of these 200 septic patients, 81 septic patients developed a new episode of AF and included in the present study. Thirty-seven patients had no past medical history of atrial fibrillation (AF) or antiarrhythmic therapy (new episode of atrial fibrillation, Group 1) and 44 had previously known episodes of atrial fibrillation and were prescribed antiarrhythmic therapy at home (Group 2). Group 2 patients had longer duration of recurrent episodes of atrial fibrillation compared to patients in Group 1 (11.07 ± 8.7 vs. 7.4 ± 6.1 days; P = 0.013). The overall ICU and in-hospital mortality rate was similar in both study groups. There was no significant difference in new stroke and pulmonary embolism (PE) between both study groups (P > 0.05).

CONCLUSION: In the present study we demonstrated no difference in morbidity and mortality rate in-ICU and after discharge between septic patients who had previous AF episodes and patients who had no previous past medical history of any cardiac arrhythmias.

Abstract

BACKGROUND: Evidence of various cardiac arrhythmias in septic patients has been demonstrated by multiple clinical reports and observations. Most cardiac arrhythmias in sepsis are new-onset and may be related to sepsis-induced myocardial dysfunction. We propose to investigate and analyze data of new-onset paroxysmal atrial fibrillation (AF) in a critically ill septic population.

METHODS: This is a retrospective epidemiologic study. We collected clinical data from two hundred septic patients who developed a new episode of atrial fibrillation during their hospitalization in General Intensive Care Unit (GICU) between January 2007 and June 2013.

RESULTS: Of these 200 septic patients, 81 septic patients developed a new episode of AF and included in the present study. Thirty-seven patients had no past medical history of atrial fibrillation (AF) or antiarrhythmic therapy (new episode of atrial fibrillation, Group 1) and 44 had previously known episodes of atrial fibrillation and were prescribed antiarrhythmic therapy at home (Group 2). Group 2 patients had longer duration of recurrent episodes of atrial fibrillation compared to patients in Group 1 (11.07 ± 8.7 vs. 7.4 ± 6.1 days; P = 0.013). The overall ICU and in-hospital mortality rate was similar in both study groups. There was no significant difference in new stroke and pulmonary embolism (PE) between both study groups (P > 0.05).

CONCLUSION: In the present study we demonstrated no difference in morbidity and mortality rate in-ICU and after discharge between septic patients who had previous AF episodes and patients who had no previous past medical history of any cardiac arrhythmias.

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Keywords

New-onset atrial fibrillation, cardiac arrhythmias, sepsis

About this article
Title

Epidemiology of new-onset paroxysmal atrial fibrillation in the General Intensive Care Unit population and after discharge from ICU. A retrospective epidemiological study

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 47, No 4 (2015)

Pages

309-314

Published online

2015-07-26

DOI

10.5603/AIT.a2015.0040

Bibliographic record

Anaesthesiol Intensive Ther 2015;47(4):309-314.

Keywords

New-onset atrial fibrillation
cardiac arrhythmias
sepsis

Authors

Leonid Koyfman
Evgeni Brotfain
Ruslan Kutz
Amit Frenkel
Andrei Schwartz
Avi Boniel
Alexander Zlotnik
Moti Klein

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