open access

Vol 46, No 4 (2014 Sep-Oct)
Original and clinical articles
Submitted: 2014-10-07
Accepted: 2014-10-07
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The prevalence of infections and colonisation with Klebsiella pneumoniae strains isolated in ICU patients

Alicja Sękowska, Eugenia Gospodarek, Krzysztof Kusza
DOI: 10.5603/AIT.2014.0045
·
Anaesthesiol Intensive Ther 2014;46(4):280-283.

open access

Vol 46, No 4 (2014 Sep-Oct)
Original and clinical articles
Submitted: 2014-10-07
Accepted: 2014-10-07

Abstract

Background: Klebsiella spp. are among the bacteria most commonly isolated from patients with infections in ICUs. The source of these infections may be the microflora of the patient or the hospital environment. Increasingly, Klebsiella strains are also being isolated from epidemic outbreaks. This situation is largely the result of widespread, irrational antibiotic use, the virulence of the bacterial strains and their ability to survive in the hospital environment. The purpose of this dissertation was to estimate the prevalence of Klebsiella pneumoniae strains isolated from patients hospitalised in a single ICU.

Methods: Seventy-eight isolates of K. pneumoniae were studied. The identification and the susceptibility to selected antibiotics were tested by an automated system, VITEK2 Compact. For the analysed strains, the production of different beta-lactamases was noted.

Results: Production of ESBL was detected in 64.1% of the K. pneumoniae strains isolated from infections and 74.4% from rectal swabs. Most of the strains were susceptible to imipenem (97.7%) and meropenem (96.1%). Sixty-nine (57.0%) of the analysed strains were identified as multidrug resistant.

Conclusion: Most of the analysed Klebsiella pneumoniae strains produced ESBL-beta-lactamases. The frequency of colonisation and infection with multidrug resistant strains of K. pneumoniae in patients hospitalised in the ICU is very high.

Abstract

Background: Klebsiella spp. are among the bacteria most commonly isolated from patients with infections in ICUs. The source of these infections may be the microflora of the patient or the hospital environment. Increasingly, Klebsiella strains are also being isolated from epidemic outbreaks. This situation is largely the result of widespread, irrational antibiotic use, the virulence of the bacterial strains and their ability to survive in the hospital environment. The purpose of this dissertation was to estimate the prevalence of Klebsiella pneumoniae strains isolated from patients hospitalised in a single ICU.

Methods: Seventy-eight isolates of K. pneumoniae were studied. The identification and the susceptibility to selected antibiotics were tested by an automated system, VITEK2 Compact. For the analysed strains, the production of different beta-lactamases was noted.

Results: Production of ESBL was detected in 64.1% of the K. pneumoniae strains isolated from infections and 74.4% from rectal swabs. Most of the strains were susceptible to imipenem (97.7%) and meropenem (96.1%). Sixty-nine (57.0%) of the analysed strains were identified as multidrug resistant.

Conclusion: Most of the analysed Klebsiella pneumoniae strains produced ESBL-beta-lactamases. The frequency of colonisation and infection with multidrug resistant strains of K. pneumoniae in patients hospitalised in the ICU is very high.

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Keywords

infection, colonization; Klebsiella, ICU

About this article
Title

The prevalence of infections and colonisation with Klebsiella pneumoniae strains isolated in ICU patients

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 46, No 4 (2014 Sep-Oct)

Pages

280-283

DOI

10.5603/AIT.2014.0045

Bibliographic record

Anaesthesiol Intensive Ther 2014;46(4):280-283.

Keywords

infection
colonization
Klebsiella
ICU

Authors

Alicja Sękowska
Eugenia Gospodarek
Krzysztof Kusza

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