open access

Vol 44, No 1 (2012 Jan-Mar)
Review articles
Published online: 2012-03-30
Submitted: 2012-03-30
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The use of opioid adjuvants in perioperative multimodal analgesia

Maciej Żukowski, Katarzyna Kotfis
Anaesthesiol Intensive Ther 2012;44(1):42-46.

open access

Vol 44, No 1 (2012 Jan-Mar)
Review articles
Published online: 2012-03-30
Submitted: 2012-03-30

Abstract

Postoperative analgesia plays a crucial role in day-case surgery. Patients expect effective pain relief after surgery, without side effects, and this may not always be possible when more complicated procedures are performed in ambulatory settings. Moreover, both surgeons and patients expect anaesthesiologists to provide an effective pain treatment service especially after ambulatory surgery, even in private practice settings. The protocols based on intravenous opioids or central neuraxial blockade are no longer appropriate, when a short, uncomplicated postoperative course is anticipated. Multimodal analgesia, combining different groups of analgesics, both opioid and non-opioid, with different mechanisms of action, and targets in central and peripheral nervous systems with minimal side effects may be an answer. In this review, we present and discuss the current status of knowledge, with special reference to the role of adjuvants to opioids in acute postoperative pain.

Abstract

Postoperative analgesia plays a crucial role in day-case surgery. Patients expect effective pain relief after surgery, without side effects, and this may not always be possible when more complicated procedures are performed in ambulatory settings. Moreover, both surgeons and patients expect anaesthesiologists to provide an effective pain treatment service especially after ambulatory surgery, even in private practice settings. The protocols based on intravenous opioids or central neuraxial blockade are no longer appropriate, when a short, uncomplicated postoperative course is anticipated. Multimodal analgesia, combining different groups of analgesics, both opioid and non-opioid, with different mechanisms of action, and targets in central and peripheral nervous systems with minimal side effects may be an answer. In this review, we present and discuss the current status of knowledge, with special reference to the role of adjuvants to opioids in acute postoperative pain.

Get Citation

Keywords

analgesia, perioperative, adjuvants; analgesics, opioids

About this article
Title

The use of opioid adjuvants in perioperative multimodal analgesia

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 44, No 1 (2012 Jan-Mar)

Pages

42-46

Published online

2012-03-30

Bibliographic record

Anaesthesiol Intensive Ther 2012;44(1):42-46.

Keywords

analgesia
perioperative
adjuvants
analgesics
opioids

Authors

Maciej Żukowski
Katarzyna Kotfis

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