open access

Vol 44, No 2 (2012 Apr-Jun)
Review articles
Published online: 2012-08-08
Submitted: 2012-07-05
Accepted: 2012-07-05
Get Citation

Strategies of empiric antibiotic therapy in severe sepsis

Wiesława Duszyńska
Anaesthesiol Intensive Ther 2012;44(2):96-103.

open access

Vol 44, No 2 (2012 Apr-Jun)
Review articles
Published online: 2012-08-08
Submitted: 2012-07-05
Accepted: 2012-07-05

Abstract

Severe sepsis and septic shock remain the leading causes of multiple organ failure and mortality in surgical intensive care units. Early antibiotic therapy recently became a challenge, because of the increased number of infections caused by multiple drug resistant bacteria, with Gram-negative bacteria such as Klebsiella pneumoniae and Pseudomonas aeruginosa being the most frequently cultured pathogens. In this review, detailed recommendations for the treatment of various infections are presented and discussed, with particular emphasis on the determination of empiric antibiotic therapy in the early stages of sepsis and localised infections.

Abstract

Severe sepsis and septic shock remain the leading causes of multiple organ failure and mortality in surgical intensive care units. Early antibiotic therapy recently became a challenge, because of the increased number of infections caused by multiple drug resistant bacteria, with Gram-negative bacteria such as Klebsiella pneumoniae and Pseudomonas aeruginosa being the most frequently cultured pathogens. In this review, detailed recommendations for the treatment of various infections are presented and discussed, with particular emphasis on the determination of empiric antibiotic therapy in the early stages of sepsis and localised infections.

Get Citation

Keywords

antibiotics, empiric therapy, sepsis

About this article
Title

Strategies of empiric antibiotic therapy in severe sepsis

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 44, No 2 (2012 Apr-Jun)

Pages

96-103

Published online

2012-08-08

Bibliographic record

Anaesthesiol Intensive Ther 2012;44(2):96-103.

Keywords

antibiotics
empiric therapy
sepsis

Authors

Wiesława Duszyńska

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