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Streptomyces pneumonia in an immunocompetent adult — a rare isolate
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Abstract
Streptomyces belongs to the Actinomycetes group of bacteria which are gram-positive non acid-fast bacilli, widely recognised for their potential to produce antimicrobials active against bacterial, mycobacterial, parasitic and fungal infections. They commonly cause cutaneous infections following traumatic inoculation. Visceral infections are relatively rare and limited to immunocompro-mised hosts. We describe a case of Streptomyces pneumonia in a healthy immunocompetent female, who when investigated for voluntary kidney donation, resulted in the isolation of Streptomyces species from bronchial wash cultures. Streptomyces, a potential pathogen in immunocompetent hosts is frequently underdiagnosed. Once isolated, both physicians and microbiologists should pay attention to differentiate true infection from contamination.
Abstract
Streptomyces belongs to the Actinomycetes group of bacteria which are gram-positive non acid-fast bacilli, widely recognised for their potential to produce antimicrobials active against bacterial, mycobacterial, parasitic and fungal infections. They commonly cause cutaneous infections following traumatic inoculation. Visceral infections are relatively rare and limited to immunocompro-mised hosts. We describe a case of Streptomyces pneumonia in a healthy immunocompetent female, who when investigated for voluntary kidney donation, resulted in the isolation of Streptomyces species from bronchial wash cultures. Streptomyces, a potential pathogen in immunocompetent hosts is frequently underdiagnosed. Once isolated, both physicians and microbiologists should pay attention to differentiate true infection from contamination.
Keywords
Streptomyces; pneumonia; immunocompetent; visceral infections
About this articleTitle
Streptomyces pneumonia in an immunocompetent adult — a rare isolate
Journal
Advances in Respiratory Medicine
Issue
Article type
Case report
Published online
2020-11-20
DOI
10.5603/ARM.a2020.0171
Keywords
Streptomyces
pneumonia
immunocompetent
visceral infections
Authors
Muniza Bai
Mahesh Babu Vemuri
Madhusmita Mohanty Mohapatra
Shahana Mp
Sujatha Sistla
Radha Sugumaran
References (10)- McNeil MM, Brown JM, Jarvis WR, et al. Comparison of species distribution and antimicrobial susceptibility of aerobic actinomycetes from clinical specimens. Rev Infect Dis. 1990; 12(5): 778–783.
- Watve MG, Tickoo R, Jog MM, et al. How many antibiotics are produced by the genus Streptomyces? Arch Microbiol. 2001; 176(5): 386–390.
- Dunne EF, Burman WJ, Wilson ML. Streptomyces pneumonia in a patient with human immunodeficiency virus infection: case report and review of the literature on invasive streptomyces infections. Clin Infect Dis. 1998; 27(1): 93–96.
- Ekkelenkamp MB, de Jong W, Hustinx W, et al. Streptomyces thermovulgaris bacteremia in Crohn's disease patient. Emerg Infect Dis. 2004; 10(10): 1883–1885.
- Carey J, Motyl M, Perlman DC. Catheter-related bacteremia due to Streptomyces in a patient receiving holistic infusions. Emerg Infect Dis. 2001; 7(6): 1043–1045.
- Mossad SB, Tomford JW, Stewart R, et al. Case report of streptomyces endocarditis of a prosthetic aortic valve. J Clin Microbiol. 1995; 33(12): 3335–3337.
- Kofteridis DP, Maraki S, Scoulica E, et al. Streptomyces pneumonia in an immunocompetent patient: a case report and literature review. Diagn Microbiol Infect Dis. 2007; 59(4): 459–462.
- Kapadia M, Rolston KVI, Han XY. Invasive streptomyces infections: six cases and literature review. Am J Clin Pathol. 2007; 127(4): 619–624.
- Ataiekhorasgani M, Jafaripozve N, Zaerin O. Streptomyces infection in Cushing syndrome: A case report and literature review. Adv Biomed Res. 2014; 3: 26.
- Patel JB, Wallace RJ, Brown-Elliott BA, et al. Sequence-Based Identification of Aerobic Actinomycetes. Journal of Clinical Microbiology. 2004; 42(6): 2530–2540.