open access

Vol 89, No 2 (2021)
Case report
Submitted: 2020-05-27
Accepted: 2020-07-30
Published online: 2021-01-29
Get Citation

Malignant pleural effusion from squamous cell carcinoma of the vulva: extremely rare metastatic pattern of a rarely metastasizing cancer

Zeeshan Hafeez1, Sarwat I. Gilani2, Lying Han2, Gizelka David-West3, Oleg Epelbaum1
DOI: 10.5603/ARM.a2020.0182
·
Pubmed: 33559117
·
Adv Respir Med 2021;89(2):207-210.
Affiliations
  1. Division of Pulmonary, Critical Care and Sleep Medicine, Westchester Medical Center, Valhalla, New York, United States
  2. Department of Pathology Westchester Medical Center, Valhalla, NY, USA
  3. Division of Gynecological Oncology Westchester Medical Center, Valhalla, NY, USA

open access

Vol 89, No 2 (2021)
CASE REPORTS
Submitted: 2020-05-27
Accepted: 2020-07-30
Published online: 2021-01-29

Abstract

The discovery of a malignant pleural effusion indicates metastatic disease and thus invariably results in the highest possible cancer stage. Although the female reproductive tract overall is a common primary tumor site giving rise to malignant pleural effusion, vulvar carcinoma stands out for its propensity for locoregional spread rather than distant metastasis. Our case contributes to the extremely limited number of published descriptions of thoracic involvement by vulvar carcinoma, with malignant pleural effusion being a particularly unusual pattern.

Abstract

The discovery of a malignant pleural effusion indicates metastatic disease and thus invariably results in the highest possible cancer stage. Although the female reproductive tract overall is a common primary tumor site giving rise to malignant pleural effusion, vulvar carcinoma stands out for its propensity for locoregional spread rather than distant metastasis. Our case contributes to the extremely limited number of published descriptions of thoracic involvement by vulvar carcinoma, with malignant pleural effusion being a particularly unusual pattern.

Get Citation

Keywords

vulvar carcinoma; squamous cell carcinoma; malignant pleural effusion; pleural metastases

About this article
Title

Malignant pleural effusion from squamous cell carcinoma of the vulva: extremely rare metastatic pattern of a rarely metastasizing cancer

Journal

Advances in Respiratory Medicine

Issue

Vol 89, No 2 (2021)

Article type

Case report

Pages

207-210

Published online

2021-01-29

DOI

10.5603/ARM.a2020.0182

Pubmed

33559117

Bibliographic record

Adv Respir Med 2021;89(2):207-210.

Keywords

vulvar carcinoma
squamous cell carcinoma
malignant pleural effusion
pleural metastases

Authors

Zeeshan Hafeez
Sarwat I. Gilani
Lying Han
Gizelka David-West
Oleg Epelbaum

References (15)
  1. Feller-Kopman D, Light R, Feller-Kopman D, et al. Pleural disease. N Engl J Med. 2018; 378(8): 740–751.
  2. Clive AO, Kahan BC, Hooper CE, et al. Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score. Thorax. 2014; 69(12): 1098–1104.
  3. Wang JG, Cox PG. A woman in her 30s with a history of cervical cancer presents with shortness of Breath and pleuritic chest pain. Chest. 2017; 151(5): e115–e118.
  4. Hiensch R, Meinhof K, Leytin A, et al. Clinically occult primary fallopian tube carcinoma presenting as a malignant pleural effusion. Clin Respir J. 2017; 11(6): 1086–1090.
  5. Siegel RL, Miller KD, Fedewa SA, et al. Cancer statistics, 2017. CA Cancer J Clin. 2017; 67(1): 7–30.
  6. Weinberg D, Gomez-Martinez RA. Vulvar cancer. Obstet Gynecol Clin North Am. 2019; 46(1): 125–135.
  7. Ataseven B, Chiva LM, Harter P, et al. FIGO stage IV epithelial ovarian, fallopian tube and peritoneal cancer revisited. Gynecol Oncol. 2016; 142(3): 597–607.
  8. Porcel JM, Esquerda A, Vives M, et al. Etiology of pleural effusions: analysis of more than 3,000 consecutive thoracenteses. Arch Bronconeumol. 2014; 50(5): 161–165.
  9. Arnold DT, De Fonseka D, Perry S, et al. Investigating unilateral pleural effusions: the role of cytology. Eur Respir J. 2018; 52(5).
  10. Dursun P, Ayhan A, Tarhan NC, et al. Cerebellar metastasis in squamous cell vulvar carcinoma. Arch Gynecol Obstet. 2009; 279(1): 69–71.
  11. Vicus D, Korach J, Friedman E, et al. Vulvar cancer metastatic to the breast. Gynecol Oncol. 2006; 103(3): 1144–1146.
  12. Linder R, Lauterbach R, Reiss A. A case of recurrent vulvar carcinoma with cardiac metastasis: case report and review of the literature. Int J Gynecol Pathol. 2020; 39(4): 400–403.
  13. Prieske K, Haeringer N, Grimm D, et al. Patterns of distant metastases in vulvar cancer. Gynecol Oncol. 2016; 142(3): 427–434.
  14. Steele DM, Hegstrand LR, Julian TM, et al. An unusual presentation of metastatic squamous cell carcinoma of the vulva. Gynecol Oncol. 1990; 39(2): 218–220.
  15. Erra S, Patrucco G, Speranza G, et al. Unusual pleural effusion from vulvar squamous cell carcinoma: report of a case and review of the literature. Pathologica. 2016; 108: 148–150.

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