open access

Vol 89, No 2 (2021)
Case report
Submitted: 2020-05-22
Accepted: 2020-10-17
Published online: 2021-02-03
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Double carbapenem regimen used as salvage therapy to treat multidrug-resistant Klebsiella pneumoniae causing ventilator-associated pneumonia

Mandeep Singh1, Lakhvir Kaur1, Renuka Bajaj2, Sumeet Arodhia2
DOI: 10.5603/ARM.a2020.0195
·
Pubmed: 33559119
·
Adv Respir Med 2021;89(2):203-206.
Affiliations
  1. Pulmonary Medicine, Amandeep Medicity Hospital, Amritsar, India
  2. Amandeep Medicity Hospital, Amritsar, India

open access

Vol 89, No 2 (2021)
CASE REPORTS
Submitted: 2020-05-22
Accepted: 2020-10-17
Published online: 2021-02-03

Abstract

Carbapenemase-producing Klebsiella pneumoniae is an emerging threat worldwide. The appropriate therapy for infections due to these multidrug-resistant pathogens is not well defined and depends upon the susceptibilities of individual isolates, and the choices are often severely limited. We report a case of a 8-year-old male child with ARDS with left-sided tubercular pleural effusion who developed ventilator-associated pneumonia due to multidrug-resistant Klebsiella pneumoniae treated successfully with a regimen comprising a combination of colistin and double carbapenem.

Abstract

Carbapenemase-producing Klebsiella pneumoniae is an emerging threat worldwide. The appropriate therapy for infections due to these multidrug-resistant pathogens is not well defined and depends upon the susceptibilities of individual isolates, and the choices are often severely limited. We report a case of a 8-year-old male child with ARDS with left-sided tubercular pleural effusion who developed ventilator-associated pneumonia due to multidrug-resistant Klebsiella pneumoniae treated successfully with a regimen comprising a combination of colistin and double carbapenem.

Get Citation

Keywords

double carbapenem; ventilator associated pneumonia; Klebsiella pneumoniae

About this article
Title

Double carbapenem regimen used as salvage therapy to treat multidrug-resistant Klebsiella pneumoniae causing ventilator-associated pneumonia

Journal

Advances in Respiratory Medicine

Issue

Vol 89, No 2 (2021)

Article type

Case report

Pages

203-206

Published online

2021-02-03

DOI

10.5603/ARM.a2020.0195

Pubmed

33559119

Bibliographic record

Adv Respir Med 2021;89(2):203-206.

Keywords

double carbapenem
ventilator associated pneumonia
Klebsiella pneumoniae

Authors

Mandeep Singh
Lakhvir Kaur
Renuka Bajaj
Sumeet Arodhia

References (11)
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  9. Daikos GL, Panagiotakopoulou A, Tzelepi E, et al. Activity of imipenem against VIM-1 metallo-beta-lactamase-producing Klebsiella pneumoniae in the murine thigh infection model. Clin Microbiol Infect. 2007; 13(2): 202–205.
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