open access

Vol 88, No 5 (2020)
Research paper
Submitted: 2020-03-13
Accepted: 2020-05-26
Published online: 2020-10-24
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Exposure to stressful life events among patients with chronic obstructive pulmonary disease: a prospective study

Mohammad Ali Zohal1, Sima Rafiei21, Nafise Rastgoo1, sanaz Jamshidi1
DOI: 10.5603/ARM.a2020.0122
·
Pubmed: 33169807
·
Adv Respir Med 2020;88(5):377-382.
Affiliations
  1. Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin
  2. Social Determinants of Health Research Center, Qazvin University of Medical Sciences, Qazvin, Iran

open access

Vol 88, No 5 (2020)
ORIGINAL PAPERS
Submitted: 2020-03-13
Accepted: 2020-05-26
Published online: 2020-10-24

Abstract

Introduction: Although depression and anxiety have been widely investigated among patients with chronic obstructive pulmonary disease (COPD), experiencing stressful life events and its effect on increasing risk of exacerbations was rarely assessed. This study aimed to clarify the association between facing with stressful events among COPD patients and their disease severity leading to hospitalization.
Material and methods: A prospective study was conducted among 128 COPD patients from the population of Qazvin, a north-west, industrialized city of Iran from December 2017 to December 2018. Patients were followed up for one-year and their related measures were gathered. To compare variables among patients stratified by reporting stressful life conditions, Pearson’s chi-square and Fisher’s exact tests were used. Furthermore, to assess the effect of several covariates on the response variable, a logistic regression modelling was applied. Results were reported in form of odds ratios and their 95% confidence intervals. Results: Study findings affirmed that patients who had experienced stressful situation had lower BMI, were retired, experienced more frequent exacerbations, and reported higher levels of anxiety/ depression. Moreover, those with stressful conditions were among current or former smokers (p < 0.05). Logistic regression analysis revealed that facing with stressful situations was significantly associated with the severity of COPD disease (OR 1.9; 95% CI 2.5 to 5.6), smoking habit (OR 2.8; 95% CI 1.6 to 4.2; OR 1.5; 95% CI 1.4 to 2.2), and hospitalization during one-year follow up (OR 1.2; 95% CI 1 to 3.3).
Conclusions: To improve health outcomes of COPD patients, close attention should be given to their psychological disorder and appropriate strategies should be applied to reduce patients’ exposure to stressful life events and subsequent anxieties.

Abstract

Introduction: Although depression and anxiety have been widely investigated among patients with chronic obstructive pulmonary disease (COPD), experiencing stressful life events and its effect on increasing risk of exacerbations was rarely assessed. This study aimed to clarify the association between facing with stressful events among COPD patients and their disease severity leading to hospitalization.
Material and methods: A prospective study was conducted among 128 COPD patients from the population of Qazvin, a north-west, industrialized city of Iran from December 2017 to December 2018. Patients were followed up for one-year and their related measures were gathered. To compare variables among patients stratified by reporting stressful life conditions, Pearson’s chi-square and Fisher’s exact tests were used. Furthermore, to assess the effect of several covariates on the response variable, a logistic regression modelling was applied. Results were reported in form of odds ratios and their 95% confidence intervals. Results: Study findings affirmed that patients who had experienced stressful situation had lower BMI, were retired, experienced more frequent exacerbations, and reported higher levels of anxiety/ depression. Moreover, those with stressful conditions were among current or former smokers (p < 0.05). Logistic regression analysis revealed that facing with stressful situations was significantly associated with the severity of COPD disease (OR 1.9; 95% CI 2.5 to 5.6), smoking habit (OR 2.8; 95% CI 1.6 to 4.2; OR 1.5; 95% CI 1.4 to 2.2), and hospitalization during one-year follow up (OR 1.2; 95% CI 1 to 3.3).
Conclusions: To improve health outcomes of COPD patients, close attention should be given to their psychological disorder and appropriate strategies should be applied to reduce patients’ exposure to stressful life events and subsequent anxieties.

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Keywords

anxiety; depression; stressful life event; chronic obstructive pulmonary disease; severity

About this article
Title

Exposure to stressful life events among patients with chronic obstructive pulmonary disease: a prospective study

Journal

Advances in Respiratory Medicine

Issue

Vol 88, No 5 (2020)

Article type

Research paper

Pages

377-382

Published online

2020-10-24

DOI

10.5603/ARM.a2020.0122

Pubmed

33169807

Bibliographic record

Adv Respir Med 2020;88(5):377-382.

Keywords

anxiety
depression
stressful life event
chronic obstructive pulmonary disease
severity

Authors

Mohammad Ali Zohal
Sima Rafiei
Nafise Rastgoo
sanaz Jamshidi

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