open access

Vol 87, No 6 (2019)
CASE REPORTS
Published online: 2020-01-14
Submitted: 2019-08-06
Accepted: 2019-10-05
Get Citation

Not everything is what it seems: malignant pleural mesothelioma mimicking lung cancer

Elena Prisciandaro, Lara Girelli, Cristiano Rampinelli, Mariacristina Ghioni, Lorenzo Spaggiari
DOI: 10.5603/ARM.2019.0065
·
Pubmed: 31970729
·
Adv Respir Med 2019;87(6):265-267.

open access

Vol 87, No 6 (2019)
CASE REPORTS
Published online: 2020-01-14
Submitted: 2019-08-06
Accepted: 2019-10-05

Abstract

Malignant pleural mesothelioma usually arises from the pleural surface and progressively encases the lungs. Pulmonary involvement generally occurs at an advanced stage, while intraparenchymal nodules, in the absence of pleural lesions, constitute a less frequent presentation. We describe the case of a patient with multiple bilateral pulmonary nodules, mediastinal lymphadenopathies and left pleural effusion in the absence of pleural lesions, simulating advanced stage lung cancer. Thoracoscopic inspection did not detect any lesions. Pathological examination on one pulmonary nodule revealed malignant pleural mesothelioma. Despite its rarity, intraparenchymal malignant pleural mesothelioma should always be taken into account, when  lung nodules are present, to prevent misdiagnosis and avoid delayed treatment

Abstract

Malignant pleural mesothelioma usually arises from the pleural surface and progressively encases the lungs. Pulmonary involvement generally occurs at an advanced stage, while intraparenchymal nodules, in the absence of pleural lesions, constitute a less frequent presentation. We describe the case of a patient with multiple bilateral pulmonary nodules, mediastinal lymphadenopathies and left pleural effusion in the absence of pleural lesions, simulating advanced stage lung cancer. Thoracoscopic inspection did not detect any lesions. Pathological examination on one pulmonary nodule revealed malignant pleural mesothelioma. Despite its rarity, intraparenchymal malignant pleural mesothelioma should always be taken into account, when  lung nodules are present, to prevent misdiagnosis and avoid delayed treatment

Get Citation

Keywords

malignant pleural mesothelioma, differential diagnosis, lung cancer, intraparenchymal mesothelioma, lung nodule

About this article
Title

Not everything is what it seems: malignant pleural mesothelioma mimicking lung cancer

Journal

Advances in Respiratory Medicine

Issue

Vol 87, No 6 (2019)

Pages

265-267

Published online

2020-01-14

DOI

10.5603/ARM.2019.0065

Pubmed

31970729

Bibliographic record

Adv Respir Med 2019;87(6):265-267.

Keywords

malignant pleural mesothelioma
differential diagnosis
lung cancer
intraparenchymal mesothelioma
lung nodule

Authors

Elena Prisciandaro
Lara Girelli
Cristiano Rampinelli
Mariacristina Ghioni
Lorenzo Spaggiari

References (3)
  1. Nind NR, Attanoos RL, Gibbs AR. Unusual intraparenchymal growth patterns of malignant pleural mesothelioma. Histopathology. 2003; 42(2): 150–155.
  2. Larsen BT, Klein JRH, Hornychová H, et al. Diffuse intrapulmonary malignant mesothelioma masquerading as interstitial lung disease: a distinctive variant of mesothelioma. Am J Surg Pathol. 2013; 37(10): 1555–1564.
  3. Detterbeck FC, Boffa DJ, Kim AW, et al. The Eighth Edition Lung Cancer Stage Classification. Chest. 2017; 151(1): 193–203.

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