open access

Vol 87, No 6 (2019)
REVIEWS
Published online: 2020-01-14
Submitted: 2019-07-20
Accepted: 2019-12-02
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Atypical manifestations of granulomatosis with polyangiitis: the diagnostic challenge for pulmonologists

Amelia Szymanowska-Narloch, Dariusz Gawryluk, Katarzyna Błasińska-Przerwa, Alicja Siemińska
DOI: 10.5603/ARM.2019.0062
·
Pubmed: 31970726
·
Adv Respir Med 2019;87(6):244-253.

open access

Vol 87, No 6 (2019)
REVIEWS
Published online: 2020-01-14
Submitted: 2019-07-20
Accepted: 2019-12-02

Abstract

This is a review considering atypical manifestations of granulomatosis with polyangiitis (GPA). Virtually any organ can be affected, and in some patients, GPA can manifest unusually. Since thoracic involvement of GPA often predominates, the first who might be expected to establish a diagnosis are pulmonary specialists. We would like to familiarize pulmonary specialists with several extra-ELK (E: ear-nose-throat; L: lung; K: kidney) involvements of the disease. We describe sites rarely affected by GPA like the breast, skeletal system, orbit and eye, heart and vessels, central nervous system, urogenital system as well as endocrine and gastrointestinal tract involvement.

Abstract

This is a review considering atypical manifestations of granulomatosis with polyangiitis (GPA). Virtually any organ can be affected, and in some patients, GPA can manifest unusually. Since thoracic involvement of GPA often predominates, the first who might be expected to establish a diagnosis are pulmonary specialists. We would like to familiarize pulmonary specialists with several extra-ELK (E: ear-nose-throat; L: lung; K: kidney) involvements of the disease. We describe sites rarely affected by GPA like the breast, skeletal system, orbit and eye, heart and vessels, central nervous system, urogenital system as well as endocrine and gastrointestinal tract involvement.

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Keywords

granulomatosis with polyangiitis, atypical manifestations, diagnosis, therapy, vasculitis, breast, skeletal system

About this article
Title

Atypical manifestations of granulomatosis with polyangiitis: the diagnostic challenge for pulmonologists

Journal

Advances in Respiratory Medicine

Issue

Vol 87, No 6 (2019)

Pages

244-253

Published online

2020-01-14

DOI

10.5603/ARM.2019.0062

Pubmed

31970726

Bibliographic record

Adv Respir Med 2019;87(6):244-253.

Keywords

granulomatosis with polyangiitis
atypical manifestations
diagnosis
therapy
vasculitis
breast
skeletal system

Authors

Amelia Szymanowska-Narloch
Dariusz Gawryluk
Katarzyna Błasińska-Przerwa
Alicja Siemińska

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