open access

Vol 86, No 5 (2018)
LETTERS
Published online: 2018-10-30
Submitted: 2018-09-18
Accepted: 2018-09-26
Get Citation

Chronic obstructive pulmonary disease and sacubitril: explore the role of neprilysin before its inhibition

Eftychios Siniorakis, Spyridon Arvanitakis, Maximilianos Elkouris, Stamatia Kalogirou, Dimitrios Veldekis, Sotiria Limberi
DOI: 10.5603/ARM.2018.0041
·
Pubmed: 30378655
·
Adv Respir Med 2018;86(5):255-256.

open access

Vol 86, No 5 (2018)
LETTERS
Published online: 2018-10-30
Submitted: 2018-09-18
Accepted: 2018-09-26

Abstract

Not available

Abstract

Not available
Get Citation
About this article
Title

Chronic obstructive pulmonary disease and sacubitril: explore the role of neprilysin before its inhibition

Journal

Advances in Respiratory Medicine

Issue

Vol 86, No 5 (2018)

Pages

255-256

Published online

2018-10-30

DOI

10.5603/ARM.2018.0041

Pubmed

30378655

Bibliographic record

Adv Respir Med 2018;86(5):255-256.

Authors

Eftychios Siniorakis
Spyridon Arvanitakis
Maximilianos Elkouris
Stamatia Kalogirou
Dimitrios Veldekis
Sotiria Limberi

References (10)
  1. Packer M, McMurray JJV, Desai AS, et al. PARADIGM-HF Investigators and Coordinators, PARADIGM-HF Investigators and Committees. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014; 371(11): 993–1004.
  2. Liczek M, Panek I, Damiański P, et al. Neprilysin inhibitors as a new approach in the treatment of right heart failure in the course of chronic obstructive pulmonary disease. Adv Respir Med. 2018 [Epub ahead of print].
  3. Wick MJ, Buesing EJ, Wehling CA, et al. Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011; 183(3): 330–340.
  4. Karoor V, Oka M, Walchak SJ, et al. Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism. Hypertension. 2013; 61(4): 921–930.
  5. Broadley KJ, Blair AE, Kidd EJ, et al. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity. J Pharmacol Exp Ther. 2010; 335(3): 681–692.
  6. Ricciardolo FLM, Sabatini F, Sorbello V, et al. Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD. Thorax. 2013; 68(9): 803–811.
  7. Millucci L, Paccagnini E, Ghezzi L, et al. Different factors affecting human ANP amyloid aggregation and their implications in congestive heart failure. PLoS One. 2011; 6(7): e21870.
  8. Goudis CA. Chronic obstructive pulmonary disease and atrial fibrillation: An unknown relationship. J Cardiol. 2017; 69(5): 699–705.
  9. Dodd JW. Lung disease as a determinant of cognitive decline and dementia. Alzheimers Res Ther. 2015; 7(1): 32.
  10. Bu XL, Cao GQ, Shen LL, et al. Serum Amyloid-Beta Levels are Increased in Patients with Chronic Obstructive Pulmonary Disease. Neurotox Res. 2015; 28(4): 346–351.

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