open access

Vol 86, No 5 (2018)
CASE REPORTS
Published online: 2018-10-30
Submitted: 2018-07-09
Accepted: 2018-10-08
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Lung transplantation as a viable option of treatment for pulmonary veno-occlusive disease

Marek Ochman, Maciej Urlik, Zofia Tatoj, Marta Wajda-Pokrontka, Fryderyk Zawadzki, Magdalena Latos, Marian Zembala
DOI: 10.5603/ARM.2018.0040
·
Pubmed: 30378654
·
Adv Respir Med 2018;86(5):249-254.

open access

Vol 86, No 5 (2018)
CASE REPORTS
Published online: 2018-10-30
Submitted: 2018-07-09
Accepted: 2018-10-08

Abstract

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by alteration of pulmonary veins. Many clinical and hemodynamic similarities to idiopathic pulmonary arterial hypertension (IPAH) may cause diagnostic and therapeutic difficulties. This case report is about a patient with PVOD, whose first symptoms of the disease occurred after infectious mononucleosis. Patient was administered with prostacycline (PGI2) mimetic (Treprostinil), what made qualification process and lung transplantation possible. Despite more and more knowledge about causes, ethiopathogenesis and changes in pulmonary veins on molecular level, lung transplantation is the only successful therapeutic option for patients suffering from PVOD.

Abstract

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by alteration of pulmonary veins. Many clinical and hemodynamic similarities to idiopathic pulmonary arterial hypertension (IPAH) may cause diagnostic and therapeutic difficulties. This case report is about a patient with PVOD, whose first symptoms of the disease occurred after infectious mononucleosis. Patient was administered with prostacycline (PGI2) mimetic (Treprostinil), what made qualification process and lung transplantation possible. Despite more and more knowledge about causes, ethiopathogenesis and changes in pulmonary veins on molecular level, lung transplantation is the only successful therapeutic option for patients suffering from PVOD.

Get Citation

Keywords

pulmonary veno-occlusive disease, lung transplantation, idiopathic pulmonary arterial hypertension

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About this article
Title

Lung transplantation as a viable option of treatment for pulmonary veno-occlusive disease

Journal

Advances in Respiratory Medicine

Issue

Vol 86, No 5 (2018)

Pages

249-254

Published online

2018-10-30

DOI

10.5603/ARM.2018.0040

Pubmed

30378654

Bibliographic record

Adv Respir Med 2018;86(5):249-254.

Keywords

pulmonary veno-occlusive disease
lung transplantation
idiopathic pulmonary arterial hypertension

Authors

Marek Ochman
Maciej Urlik
Zofia Tatoj
Marta Wajda-Pokrontka
Fryderyk Zawadzki
Magdalena Latos
Marian Zembala

References (18)
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