open access

Vol 86, No 2 (2018)
REVIEWS
Published online: 2018-04-30
Submitted: 2017-10-10
Accepted: 2018-02-26
Get Citation

Can vitamin D help in achieving asthma control? Vitamin D ”revisited’’: an updated insight

Izabela Szymczak, Rafal Pawliczak
DOI: 10.5603/ARM.2018.0015
·
Pubmed: 29709052
·
Adv Respir Med 2018;86(2):103-109.

open access

Vol 86, No 2 (2018)
REVIEWS
Published online: 2018-04-30
Submitted: 2017-10-10
Accepted: 2018-02-26

Abstract

Asthma — a prolonged respiratory disease related with hyper-responsiveness and increased inflammation of airways; affects
millions peoples worldwide. Vitamin D possess anti-inflammatory and immunomodulatory activities. Its deficiency (the level less
than 20 ng/mL in the serum) is found to be related to occurrence of pulmonary diseases including bacterial and viral infections and
asthma. Some studies indicate that low levels of vitamin D in the serum are related to reduced lung function and increased airway
inflammation as well as overall poor results in asthmatic patients. Thus, it provides positive relation between vitamin D and asthma.
Increased prevalence of asthma over the past decades causes elevated interest in vitamin D supplementation that is even reported
as a ,,potential therapeutic option’’. Unfortunately, results of clinical trials are inconsistent and do not provide supportive information
about positive role of vitamin D in asthma. Little or even no effect of supplementation of vitamin D in improvement of onset, symptoms
or progression of asthma was found in comprehensive interventional studies in adults, children and pregnant woman. This review
critically summarized the last years evidence of a relation between vitamin D and asthma in adults, children and pregnant women.

Abstract

Asthma — a prolonged respiratory disease related with hyper-responsiveness and increased inflammation of airways; affects
millions peoples worldwide. Vitamin D possess anti-inflammatory and immunomodulatory activities. Its deficiency (the level less
than 20 ng/mL in the serum) is found to be related to occurrence of pulmonary diseases including bacterial and viral infections and
asthma. Some studies indicate that low levels of vitamin D in the serum are related to reduced lung function and increased airway
inflammation as well as overall poor results in asthmatic patients. Thus, it provides positive relation between vitamin D and asthma.
Increased prevalence of asthma over the past decades causes elevated interest in vitamin D supplementation that is even reported
as a ,,potential therapeutic option’’. Unfortunately, results of clinical trials are inconsistent and do not provide supportive information
about positive role of vitamin D in asthma. Little or even no effect of supplementation of vitamin D in improvement of onset, symptoms
or progression of asthma was found in comprehensive interventional studies in adults, children and pregnant woman. This review
critically summarized the last years evidence of a relation between vitamin D and asthma in adults, children and pregnant women.

Get Citation

Keywords

asthma, vitamin D, vitamin D deficiency, vitamin D supplementation

About this article
Title

Can vitamin D help in achieving asthma control? Vitamin D ”revisited’’: an updated insight

Journal

Advances in Respiratory Medicine

Issue

Vol 86, No 2 (2018)

Pages

103-109

Published online

2018-04-30

DOI

10.5603/ARM.2018.0015

Pubmed

29709052

Bibliographic record

Adv Respir Med 2018;86(2):103-109.

Keywords

asthma
vitamin D
vitamin D deficiency
vitamin D supplementation

Authors

Izabela Szymczak
Rafal Pawliczak

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