Diffuse alveolar haemorrhage complicated by pulmonary embolism — problems with treatment

Justyna Fijołek; Elzbieta Wiatr; Lilia Jakubowska; Malgorzata Polubiec-Kownacka; Pawel Kuca; Kazimierz Roszkowski-Sliz

doi:10.5603/ARM.2017.0056

Vol 85, No 6 (2017)

CASE REPORTS

Published online: 2017-12-13

Submitted: 2017-07-21

Accepted: 2017-10-18

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Diffuse alveolar haemorrhage complicated by pulmonary embolism — problems with treatment

Justyna Fijołek, Elzbieta Wiatr, Lilia Jakubowska, Malgorzata Polubiec-Kownacka, Pawel Kuca, Kazimierz Roszkowski-Sliz

DOI: 10.5603/ARM.2017.0056

Adv Respir Med 2017;85(6):328-332.

Vol 85, No 6 (2017)

CASE REPORTS

Published online: 2017-12-13

Submitted: 2017-07-21

Accepted: 2017-10-18

Abstract

Diffuse alveolar haemorrhage (DAH) refers to a clinical syndrome resulting from injury of the alveolar capillaries, arterioles and venules leading to red blood cel accumulation in the distal air spaces. The conditions associated with DAH and underlying disease determine the prognosis and the treatment regimen. The coexistence of DAH with venous thromboembolism (VTE) is a seroius problem for clinicians and poses a challenge in the therapeutic management. We describe a young patient who developed massive DAH in the course of anti-glomerular basement membrane (anti-GBM) disease (formerly called Goodpasture’s syndrome) complicated by pulmonary embolism (PE).