open access

Vol 85, No 1 (2017)
CASE REPORTS
Submitted: 2017-02-13
Accepted: 2017-02-13
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Tropical pulmonary eosinophilia: effect of addition of corticosteroids after failure of diethylcarbamazine therapy

Manu Madan, Pawan Gupta, Richa Mittal, Sunil K. Chhabra
DOI: 10.5603/ARM.2017.0010
·
Adv Respir Med 2017;85(1):51-54.

open access

Vol 85, No 1 (2017)
CASE REPORTS
Submitted: 2017-02-13
Accepted: 2017-02-13

Abstract

Successful response in diethylcarbamazine (DEC) therapy in tropical pulmonary eosinophilia (TPE) is not universal with a 20–40% failure rates in chronic cases. Corticosteroids have been used in such patients. However, their role in management remains ill-defined. A patient of TPE with incomplete clinical, haematological and physiological response to a standard 3 weeks DEC therapy received additional corticosteroids for the next two cycles, after which complete remission occurred. However, there was a relapse two months later with evidence of a chronic state requiring further treatment with corticosteroids with good response.

Abstract

Successful response in diethylcarbamazine (DEC) therapy in tropical pulmonary eosinophilia (TPE) is not universal with a 20–40% failure rates in chronic cases. Corticosteroids have been used in such patients. However, their role in management remains ill-defined. A patient of TPE with incomplete clinical, haematological and physiological response to a standard 3 weeks DEC therapy received additional corticosteroids for the next two cycles, after which complete remission occurred. However, there was a relapse two months later with evidence of a chronic state requiring further treatment with corticosteroids with good response.

Get Citation

Keywords

tropical pulmonary eosinophilia, diethylcarbamazine, corticosteroids

About this article
Title

Tropical pulmonary eosinophilia: effect of addition of corticosteroids after failure of diethylcarbamazine therapy

Journal

Advances in Respiratory Medicine

Issue

Vol 85, No 1 (2017)

Pages

51-54

DOI

10.5603/ARM.2017.0010

Bibliographic record

Adv Respir Med 2017;85(1):51-54.

Keywords

tropical pulmonary eosinophilia
diethylcarbamazine
corticosteroids

Authors

Manu Madan
Pawan Gupta
Richa Mittal
Sunil K. Chhabra

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