open access

Vol 85, No 2 (2017)
CASE REPORTS
Published online: 2017-03-12
Submitted: 2016-12-31
Accepted: 2017-02-28
Get Citation

Massive nasal polyposis in a patient with newly diagnosed cystic fibrosis

Małgorzata Olszowiec-Chlebna, Krzysztof Trzciński, Iwona Stelmach
DOI: 10.5603/ARM.2017.0019
·
Pubmed: 28440538
·
Adv Respir Med 2017;85(2):121-123.

open access

Vol 85, No 2 (2017)
CASE REPORTS
Published online: 2017-03-12
Submitted: 2016-12-31
Accepted: 2017-02-28

Abstract

INTRODUCTION: Cystic fibrosis (CF) — is the most common fatal autosomal recessive disease in Caucasians. A number of reports have described patients who do not meet diagnostic criteria for cystic fibrosis. Atypical or nonclassic CF is characterised by normal or borderline sweat test, pancreatic sufficiency and a monosymptomatic phenotype. For these reasons clinicians should remain alert to the possibility of the occurrence of CF.

CASE REPORT: We described a case presentation of massive nasal polyposis and recurrent sinusitis leading to the diagnosis ofcystic fibrosis in a 11-year-old male.

CONCLUSION: Our study indicates that chronic sinusitis and/or polyposis should raise the clinicians suspicion of a potential presentation of undiagnosed CF and require further investigations.

Abstract

INTRODUCTION: Cystic fibrosis (CF) — is the most common fatal autosomal recessive disease in Caucasians. A number of reports have described patients who do not meet diagnostic criteria for cystic fibrosis. Atypical or nonclassic CF is characterised by normal or borderline sweat test, pancreatic sufficiency and a monosymptomatic phenotype. For these reasons clinicians should remain alert to the possibility of the occurrence of CF.

CASE REPORT: We described a case presentation of massive nasal polyposis and recurrent sinusitis leading to the diagnosis ofcystic fibrosis in a 11-year-old male.

CONCLUSION: Our study indicates that chronic sinusitis and/or polyposis should raise the clinicians suspicion of a potential presentation of undiagnosed CF and require further investigations.

Get Citation

Keywords

cystic fibrosis, nasal polyposis, children, rhinosinusitis

About this article
Title

Massive nasal polyposis in a patient with newly diagnosed cystic fibrosis

Journal

Advances in Respiratory Medicine

Issue

Vol 85, No 2 (2017)

Pages

121-123

Published online

2017-03-12

DOI

10.5603/ARM.2017.0019

Pubmed

28440538

Bibliographic record

Adv Respir Med 2017;85(2):121-123.

Keywords

cystic fibrosis
nasal polyposis
children
rhinosinusitis

Authors

Małgorzata Olszowiec-Chlebna
Krzysztof Trzciński
Iwona Stelmach

References (9)
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  7. Yadav H, Lim KG. Chronic cough with normal sweat chloride: Phenotypic descriptions of two rare cystic fibrosis genotypes. Respir Med Case Rep. 2016; 17: 17–19.
  8. Casserly P, Harrison M, O'Connell O, et al. Nasal endoscopy and paranasal sinus computerised tomography (CT) findings in an Irish cystic fibrosis adult patient group. Eur Arch Otorhinolaryngol. 2015; 272(11): 3353–3359.
  9. Mainz JG, Schiller I, Ritschel C, et al. Sinonasal inhalation of dornase alfa in CF: A double-blind placebo-controlled cross-over pilot trial. Auris Nasus Larynx. 2011; 38(2): 220–227.

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