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open access

Vol 83, No 6 (2015)
REVIEWS
Submitted: 2015-11-10
Accepted: 2015-11-10
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Arterial and venous thromboembolism in chronic obstructive pulmonary disease: from pathogenic mechanisms to prevention and treatment

Filip Mejza, Bernd Lamprecht, Ewa Niżankowska-Mogilnicka, Anetta Undas
DOI: 10.5603/PiAP.2015.0078
·
Pneumonol Alergol Pol 2015;83(6):485-494.

open access

Vol 83, No 6 (2015)
REVIEWS
Submitted: 2015-11-10
Accepted: 2015-11-10

Abstract

Chronic obstructive pulmonary disease (COPD) affects approximately 10% of adults older than 40 years and is an important causes of disability and death in elderly subjects. A large proportion of COPD patients suffer from cardiovascular comorbidities. Thromboembolic events contribute considerably to morbidity and mortality in these subjects. This review summarizes the current evidence regarding the association of COPD with increased thromboembolic risk. We discuss multiple mechanisms potentially linking these conditions and available pharmacological interventions reducing the risk of thrombotic arterial and venous events with special attention paid to new oral anticoagulants.

Abstract

Chronic obstructive pulmonary disease (COPD) affects approximately 10% of adults older than 40 years and is an important causes of disability and death in elderly subjects. A large proportion of COPD patients suffer from cardiovascular comorbidities. Thromboembolic events contribute considerably to morbidity and mortality in these subjects. This review summarizes the current evidence regarding the association of COPD with increased thromboembolic risk. We discuss multiple mechanisms potentially linking these conditions and available pharmacological interventions reducing the risk of thrombotic arterial and venous events with special attention paid to new oral anticoagulants.

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Keywords

anticoagulants, COPD, cardiovascular, coagulation, thrombosis

About this article
Title

Arterial and venous thromboembolism in chronic obstructive pulmonary disease: from pathogenic mechanisms to prevention and treatment

Journal

Advances in Respiratory Medicine

Issue

Vol 83, No 6 (2015)

Pages

485-494

DOI

10.5603/PiAP.2015.0078

Bibliographic record

Pneumonol Alergol Pol 2015;83(6):485-494.

Keywords

anticoagulants
COPD
cardiovascular
coagulation
thrombosis

Authors

Filip Mejza
Bernd Lamprecht
Ewa Niżankowska-Mogilnicka
Anetta Undas

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