open access

Vol 83, No 6 (2015)
ORIGINAL PAPERS
Submitted: 2015-11-10
Accepted: 2015-11-10

The influence of lung volume reduction with intrabronchial valves on the quality of life of patients with heterogeneous emphysema — a prospective study

Sylwia Szlubowska, Joanna Zalewska-Puchała, Anna Majda, Piotr Kocoń, Jerzy Soja, Maciej Gnass, Ewa Pasko, Adam Ćmiel, Artur Szlubowski, Jarosław Kużdżał
DOI: 10.5603/PiAP.2015.0069
·
Pneumonol Alergol Pol 2015;83(6):418-423.

open access

Vol 83, No 6 (2015)
ORIGINAL PAPERS
Submitted: 2015-11-10
Accepted: 2015-11-10

Abstract

Introduction: A heterogeneous emphysema is one of the most severe forms of chronic obstructive pulmonary disease (COPD). In some cases, besides the standard pharmacotherapy, a new treatment option of emphysema can be used — bronchoscopic lung volume reduction (BLVR) with the use of intrabronchial valves.

Objectives: To examine the health-related quality of life (HRQoL) of patients with severe emphysema after intrabronchial valve (IBV) implantation for the treatment of one lung.

Material and methods: From 2011 to 2013 a single centre prospective observational study was performed. The study assessed the effect of the therapeutic BLVR intervention, measured by St. George Respiratory Questionnaire (SGRQ). A statistical analysis by use of Wilcoxon test for dependent variables was performed.

Results: Twenty patients were enrolled to the study (mean age 63 ± 10 years), all ex-smokers with tobacco exposure 38 ± 11.3 packyears. After 3 months of IBV treatment the average SGRQ score improved significantly in total (–12.8; p < 0.001) and in domains and the differences were for: “symptoms” (–8.5; p < 0.001), “activity” (–13.9; p < 0.001) and “influence on life”(–13.5; p < 0.002).

Conclusions: The presented study revealed a significant improvement of the quality in the life measured by SGRQ after IBV treatment for heterogeneous emphysema. For the first time our study showed the significant improvement of all three domains of SGRQ after IBV treatment.

Keywords

chronic obstructive pulmonary disease, heterogeneous emphysema, quality of life, intrabronchial valve

About this article
Title

The influence of lung volume reduction with intrabronchial valves on the quality of life of patients with heterogeneous emphysema — a prospective study

Journal

Advances in Respiratory Medicine

Issue

Vol 83, No 6 (2015)

Pages

418-423

DOI

10.5603/PiAP.2015.0069

Bibliographic record

Pneumonol Alergol Pol 2015;83(6):418-423.

Keywords

chronic obstructive pulmonary disease
heterogeneous emphysema
quality of life
intrabronchial valve

Authors

Sylwia Szlubowska
Joanna Zalewska-Puchała
Anna Majda
Piotr Kocoń
Jerzy Soja
Maciej Gnass
Ewa Pasko
Adam Ćmiel
Artur Szlubowski
Jarosław Kużdżał

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