open access

Vol 83, No 3 (2015)
REVIEWS
Submitted: 2015-04-30
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Tiotropium and its efficacy in the treatment of COPD

Maciej Kupczyk, Paweł Szepiel, Piotr Kuna
DOI: 10.5603/PiAP.2015.0037
·
Pneumonol Alergol Pol 2015;83(3):229-237.

open access

Vol 83, No 3 (2015)
REVIEWS
Submitted: 2015-04-30

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) have a negative effect on the clinical course and outcome of the disease thus causing considerable social and economic burden. As the natural course of the disease may vary, the treatment should take into account an individual approach to a patient. The appropriate treatment makes it possible to control the symptoms, improves effort tolerance and decreases the risk of exacerbations and death. Tiotropium is a muscarinic receptor antagonist, which is taken once daily, in maintenance therapy, in every stage of the disease progress. The efficacy of tiotropium in regards to exacerbations of chronic obstructive pulmonary disease has been evaluated in many clinical trials against placebo and several different active comparators. This review presents the results of those studies with the main goal to evaluate the efficacy of treatment with tiotropium in terms of prevention and course of exacerbations.

Abstract

Exacerbations of chronic obstructive pulmonary disease (COPD) have a negative effect on the clinical course and outcome of the disease thus causing considerable social and economic burden. As the natural course of the disease may vary, the treatment should take into account an individual approach to a patient. The appropriate treatment makes it possible to control the symptoms, improves effort tolerance and decreases the risk of exacerbations and death. Tiotropium is a muscarinic receptor antagonist, which is taken once daily, in maintenance therapy, in every stage of the disease progress. The efficacy of tiotropium in regards to exacerbations of chronic obstructive pulmonary disease has been evaluated in many clinical trials against placebo and several different active comparators. This review presents the results of those studies with the main goal to evaluate the efficacy of treatment with tiotropium in terms of prevention and course of exacerbations.

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Keywords

tiotropium, COPD, exacerbations

About this article
Title

Tiotropium and its efficacy in the treatment of COPD

Journal

Advances in Respiratory Medicine

Issue

Vol 83, No 3 (2015)

Pages

229-237

DOI

10.5603/PiAP.2015.0037

Bibliographic record

Pneumonol Alergol Pol 2015;83(3):229-237.

Keywords

tiotropium
COPD
exacerbations

Authors

Maciej Kupczyk
Paweł Szepiel
Piotr Kuna

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