open access

Vol 83, No 1 (2015)
CASE REPORTS
Submitted: 2015-01-08
Accepted: 2015-01-08
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Leflunomide-induced acute interstitial pneumonia in a patient treated for rheumatoid arthritis

Marta Maskey-Warzęchowska, Krzysztof Karwat, Benedykt Szczepankiewicz, Renata Langfort, Małgorzata Szołkowska, Ryszarda Chazan
DOI: 10.5603/PiAP.2015.0007
·
Pneumonol Alergol Pol 2015;83(1):50-54.

open access

Vol 83, No 1 (2015)
CASE REPORTS
Submitted: 2015-01-08
Accepted: 2015-01-08

Abstract

Leflunomide is a disease-modifying anti-rheumatic drug that is used in patients with rheumatoid arthritis (RA), who do not respond well to standard RA treatment. Leflunomide therapy may, however, be related with significant pulmonary complications in predisposed individuals. We present a patient with RA treated with leflunomide, in whom leflunomide lung injury had a fatal outcome. Potential risk factors for pulmonary complications of leflunomide treatment and the management of patients with leflunomide lung injury are discussed.

Abstract

Leflunomide is a disease-modifying anti-rheumatic drug that is used in patients with rheumatoid arthritis (RA), who do not respond well to standard RA treatment. Leflunomide therapy may, however, be related with significant pulmonary complications in predisposed individuals. We present a patient with RA treated with leflunomide, in whom leflunomide lung injury had a fatal outcome. Potential risk factors for pulmonary complications of leflunomide treatment and the management of patients with leflunomide lung injury are discussed.

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Keywords

interstitial pneumonia, rheumatoid arthritis, leflunomide

About this article
Title

Leflunomide-induced acute interstitial pneumonia in a patient treated for rheumatoid arthritis

Journal

Advances in Respiratory Medicine

Issue

Vol 83, No 1 (2015)

Pages

50-54

DOI

10.5603/PiAP.2015.0007

Bibliographic record

Pneumonol Alergol Pol 2015;83(1):50-54.

Keywords

interstitial pneumonia
rheumatoid arthritis
leflunomide

Authors

Marta Maskey-Warzęchowska
Krzysztof Karwat
Benedykt Szczepankiewicz
Renata Langfort
Małgorzata Szołkowska
Ryszarda Chazan

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