open access

Vol 82, No 6 (2014)
CASE REPORTS
Submitted: 2014-10-22
Accepted: 2014-10-22

Obliterative bronchiolitis due to inhalation of toxic gases and fumes — case report

Jolanta Winek, Jacek Zych, Renata Langfort, Kazimierz Roszkowski-Śliż
DOI: 10.5603/PiAP.2014.0076
·
Pneumonol Alergol Pol 2014;82(6):576-581.

open access

Vol 82, No 6 (2014)
CASE REPORTS
Submitted: 2014-10-22
Accepted: 2014-10-22

Abstract

Obliterative bronchiolitis is a rare pulmonary disease, characterised by narrowing and eventual obliteration of bronchioles by peribronchial and submucosal fibrosis. One of the identified causes of bronchiolitis is acute injury due to inhalation of toxic gases and fumes. Physiological criteria, essential in preliminary diagnostics, include irreversible airflow limitation, forced expiratory volume in 1 second (FEV1) < 60%, and exclusion of other causes of airflow obstruction. Surgical lung biopsy with histologic examination confirms diagnosis definitely. Prognosis of obliterative bronchiolitis, irrespective of aetiology, is rather poor, and treatment is rarely efficacious. We present a young chemist exposed to inhalation of toxic gases and fumes due to lack of usage of any personal protective equipment. He was referred to our lung disease department because of shortness of breath on exertion and irreversible airflow limitation. Definitive diagnosis of obliterative bronchiolitis was established by histological examination of specimen from open lung biopsy.

Keywords

obliterative bronchiolitis, constrictive bronchiolitis, bronchiolitis obliterans, toxic inhalation, small-airways obstruction

About this article
Title

Obliterative bronchiolitis due to inhalation of toxic gases and fumes — case report

Journal

Advances in Respiratory Medicine

Issue

Vol 82, No 6 (2014)

Pages

576-581

DOI

10.5603/PiAP.2014.0076

Bibliographic record

Pneumonol Alergol Pol 2014;82(6):576-581.

Keywords

obliterative bronchiolitis
constrictive bronchiolitis
bronchiolitis obliterans
toxic inhalation
small-airways obstruction

Authors

Jolanta Winek
Jacek Zych
Renata Langfort
Kazimierz Roszkowski-Śliż

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