open access

Vol 81, No 3 (2013)
CASE REPORTS
Submitted: 2013-04-19
Accepted: 2013-04-19
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Fibrosing mediastinitis with pulmonary hypertension as a rare complication of sarcoidosis

Monika Załęska, Katarzyna Błasińska-Przerwa, Karina Oniszh, Barbara Roszkowska-Śliż, Kazimierz Roszkowski-Śliż
Pneumonol Alergol Pol 2013;81(3):273-280.

open access

Vol 81, No 3 (2013)
CASE REPORTS
Submitted: 2013-04-19
Accepted: 2013-04-19

Abstract

Fibrosing mediastinitis is a rare disease, mostly associated with previous granulomatous diseases, such as histoplasmosis, tuberculosis, or sarcoidosis. We present a case of 42-year-old woman with sarcoidosis, who had developed fibrosing mediastinitis and pulmonary hypertension. Contrast-enhanced computer tomography showed abnormal, bilateral, solid tissues surrounding the hila and mediastinum. Magnetic resonance imaging showed: abnormal, intermediate signal tissue in the mediastinum, surrounding hila, narrowing both lower lobe arteries and both lobe bronchi, left upper lobe atelectasis, and contrast enhancement of mediastinal infiltration. The patient was treated with steroids for 14 months (initial dose of prednisone was 1 mg/kg/day, then tapered) with clinical and radiological improvement. We reviewed the literature concerning fibrosing mediastinitis. The various causes of that disorder, the radiological manifestation, and possible treatment modalities are discussed. The causes of pulmonary hypertension in our patient are another aspect of the article. It could be associated with both the fibrosing mediastinitis and the sarcoidosis.

Abstract

Fibrosing mediastinitis is a rare disease, mostly associated with previous granulomatous diseases, such as histoplasmosis, tuberculosis, or sarcoidosis. We present a case of 42-year-old woman with sarcoidosis, who had developed fibrosing mediastinitis and pulmonary hypertension. Contrast-enhanced computer tomography showed abnormal, bilateral, solid tissues surrounding the hila and mediastinum. Magnetic resonance imaging showed: abnormal, intermediate signal tissue in the mediastinum, surrounding hila, narrowing both lower lobe arteries and both lobe bronchi, left upper lobe atelectasis, and contrast enhancement of mediastinal infiltration. The patient was treated with steroids for 14 months (initial dose of prednisone was 1 mg/kg/day, then tapered) with clinical and radiological improvement. We reviewed the literature concerning fibrosing mediastinitis. The various causes of that disorder, the radiological manifestation, and possible treatment modalities are discussed. The causes of pulmonary hypertension in our patient are another aspect of the article. It could be associated with both the fibrosing mediastinitis and the sarcoidosis.

Get Citation

Keywords

fibrosing mediastinitis, sarcoidosis, pulmonary hypertension

About this article
Title

Fibrosing mediastinitis with pulmonary hypertension as a rare complication of sarcoidosis

Journal

Advances in Respiratory Medicine

Issue

Vol 81, No 3 (2013)

Pages

273-280

Bibliographic record

Pneumonol Alergol Pol 2013;81(3):273-280.

Keywords

fibrosing mediastinitis
sarcoidosis
pulmonary hypertension

Authors

Monika Załęska
Katarzyna Błasińska-Przerwa
Karina Oniszh
Barbara Roszkowska-Śliż
Kazimierz Roszkowski-Śliż

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