open access

Vol 73, No 3-4 (2005)
ORIGINAL PAPERS
Published online: 2008-02-18
Submitted: 2013-02-22
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Ocena niektórych funkcji granulocytów obojętnochłonnych u chorych na raka płuca leczonych lekami cytoredukcyjnymi

Beata Panek, Elżbieta Chyczewska, Maria Ossolińska, Wojciech Naumnik, Tomasz Izycki-Herman, Małgorzata Korniluk
Pneumonol Alergol Pol 2005;73(3-4):167-171.

open access

Vol 73, No 3-4 (2005)
ORIGINAL PAPERS
Published online: 2008-02-18
Submitted: 2013-02-22

Abstract

Lung cancer (NSCLC and SCLC) is one of most frequent carcinoma. Lung cancer is at the top of the list of cancers causing mortality in males. Many patients are qualified to chemotherapy which causes neutropenia.
The aim of this work was to evaluate the number and function of (phagocytosis, test of NBT reduction and MPO activity) of leukocytes in patients with lung cancer before chemotherapy, during leukopenia and after stimulation with granulocyte colony stimulating factor (G-CSF).
Patients with lung cancer have increased number of leukocytes before the treatment. After chemotherapy the number of leukocytes decreases. Treatment with G-CSF increases the number of leukocytes but it doesn't increase their ability to phagocytosis and to NBT reduction.
Pneumonol. Alergol. Pol. 2005, 73, 167-171.

Abstract

Lung cancer (NSCLC and SCLC) is one of most frequent carcinoma. Lung cancer is at the top of the list of cancers causing mortality in males. Many patients are qualified to chemotherapy which causes neutropenia.
The aim of this work was to evaluate the number and function of (phagocytosis, test of NBT reduction and MPO activity) of leukocytes in patients with lung cancer before chemotherapy, during leukopenia and after stimulation with granulocyte colony stimulating factor (G-CSF).
Patients with lung cancer have increased number of leukocytes before the treatment. After chemotherapy the number of leukocytes decreases. Treatment with G-CSF increases the number of leukocytes but it doesn't increase their ability to phagocytosis and to NBT reduction.
Pneumonol. Alergol. Pol. 2005, 73, 167-171.
Get Citation

Keywords

lung cancer; chemotherapy; neutropenia; GCSF

About this article
Title

Ocena niektórych funkcji granulocytów obojętnochłonnych u chorych na raka płuca leczonych lekami cytoredukcyjnymi

Journal

Advances in Respiratory Medicine

Issue

Vol 73, No 3-4 (2005)

Pages

167-171

Published online

2008-02-18

Bibliographic record

Pneumonol Alergol Pol 2005;73(3-4):167-171.

Keywords

lung cancer
chemotherapy
neutropenia
GCSF

Authors

Beata Panek
Elżbieta Chyczewska
Maria Ossolińska
Wojciech Naumnik
Tomasz Izycki-Herman
Małgorzata Korniluk

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