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Vol 75, No 1 (2007)
GUIDELINES
Published online: 2007-04-13
Submitted: 2013-02-22
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Small-cell lung cancer diagnostic and therapeutic recommendations of Polish Lung Cancer Group

Maciej Krzakowski, Tadeusz Orłowski, Kazimierz Roszkowski, Marian Reinfuss, Włodzimierz Olszewski, Rodryg Ramlau, Dariusz Kowalski, Krzysztof Konopa, Jacek Jassem, Renata Jankowska, Jerzy Kozielski, Marek Wojtukiewicz, Kazimierz Drosik, Piotr Koralewski
Pneumonol Alergol Pol 2007;75(1):88-94.

open access

Vol 75, No 1 (2007)
GUIDELINES
Published online: 2007-04-13
Submitted: 2013-02-22

Abstract

Small-cell lung cancer is characterized by an aggressive clinical course with high tendency for early dissemination. At presentation, patients are usually symptomatic and with hilar or mediastinal mass at radiography. Staging should be focused on identifying any evidence of distant spread. Chemotherapy including cisplatin and etoposide is a cornerstone of treatment for all patients. Limited-stage disease should be managed by chemotherapy combined with concurrent chest irradiation. All patients who achieve complete response should be considered for elective cranial irradiation. Surgical treatment may be used in highly selected patients with TNM stage I disease, and surgery should always be combined with chemotherapy. Extensive-stage disease should be managed by multi-agent chemotherapy alone. Long-term survivorus should undergo careful monitoring for development of a second primary tumour.

Abstract

Small-cell lung cancer is characterized by an aggressive clinical course with high tendency for early dissemination. At presentation, patients are usually symptomatic and with hilar or mediastinal mass at radiography. Staging should be focused on identifying any evidence of distant spread. Chemotherapy including cisplatin and etoposide is a cornerstone of treatment for all patients. Limited-stage disease should be managed by chemotherapy combined with concurrent chest irradiation. All patients who achieve complete response should be considered for elective cranial irradiation. Surgical treatment may be used in highly selected patients with TNM stage I disease, and surgery should always be combined with chemotherapy. Extensive-stage disease should be managed by multi-agent chemotherapy alone. Long-term survivorus should undergo careful monitoring for development of a second primary tumour.

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Keywords

small-cell lung cancer; diagnosis; staging; recommendations; chemotherapy; radiotherapy; surgical treatment

About this article
Title

Small-cell lung cancer diagnostic and therapeutic recommendations of Polish Lung Cancer Group

Journal

Advances in Respiratory Medicine

Issue

Vol 75, No 1 (2007)

Pages

88-94

Published online

2007-04-13

Bibliographic record

Pneumonol Alergol Pol 2007;75(1):88-94.

Keywords

small-cell lung cancer
diagnosis
staging
recommendations
chemotherapy
radiotherapy
surgical treatment

Authors

Maciej Krzakowski
Tadeusz Orłowski
Kazimierz Roszkowski
Marian Reinfuss
Włodzimierz Olszewski
Rodryg Ramlau
Dariusz Kowalski
Krzysztof Konopa
Jacek Jassem
Renata Jankowska
Jerzy Kozielski
Marek Wojtukiewicz
Kazimierz Drosik
Piotr Koralewski

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