Stroke as a predominant symptom at Churg-Strauss syndrome

Jolanta Winek; Jacek Zych; Elżbieta Wiatr; Karina Oniszh; Kazimierz Roszkowski-Śliż

Vol 75, No 2 (2007)

Case report

Published online: 2007-06-03

Submitted: 2013-02-22

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Stroke as a predominant symptom at Churg-Strauss syndrome

Jolanta Winek, Jacek Zych, Elżbieta Wiatr, Karina Oniszh, Kazimierz Roszkowski-Śliż

Pneumonol Alergol Pol 2007;75(2):191-196.

Vol 75, No 2 (2007)

CASE REPORTS

Published online: 2007-06-03

Submitted: 2013-02-22

Abstract

Intracerebral hemorrhage is a rare sequel of Churg-Strauss syndrome. We report a case of 55 years old man, who was admitted to the National Tuberculosis and Lung Diseases Research Institute because of paroxysmal dyspnea and persistent cough. 6 months prior to hospitalization the patient suffered from spontaneous intracerebral hemorrhage. The laboratory studies revealed: leukocytosis with 65% being eosinophils, elevated serum IgE (810 IU/ml) and pANCA titre (1:640). HRCT disclosed in both lungs several small ground glass attenuations and thickening of bronchial walls. In bronchoalveolar lavage numerous eosinophils were noted. During hospitalization episodes of dyspnea with bronchospasm improving after β2-mimetics inhalation were repeatedly observed, the findings that could suggest asthma. Based on clinical criteria of French Vasculitits Study Group, Churg-Strauss syndrome was recognized. The patient was treated with prednisone 50 mg daily with rapid regression of the respiratory symptoms and gradual normalization of the laboratory results.