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Vol 75, No 3 (2007)
ORIGINAL PAPERS
Published online: 2007-07-30
Submitted: 2013-02-22
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Prediction of exercise capacity in chronic obstructive pulmonary disease patients on the basis of maximum expiratory flow-volume curve

Marzena Trzaska-Sobczak, Władysław Pierzchała
Pneumonol Alergol Pol 2007;75(3):213-218.

open access

Vol 75, No 3 (2007)
ORIGINAL PAPERS
Published online: 2007-07-30
Submitted: 2013-02-22

Abstract

Introduction: Patients with chronic obstructive pulmonary disease (COPD) often present reduced exercise tolerance. Limitation of exercise capacity in COPD is an essential feature, which can be accurately determined by incremental cycle ergometry. The relationship between resting lung function variables and exercise capacity has been studied extensively in COPD patients. A clear relationship between resting pulmonary function testing and exercise capacity has not been established. The present study was designed to assess the accuracy of new index such as area under the maximal expiratory flow-volume curve [A(ex)] in predicting exercise capacity (expressed by maximum oxygen uptake - V’O2max and maximal mechanical work - Wmax) in COPD patients.
Material and methods: The study was performed on 41 patients with mild - to severe COPD (FEV1, 57.2 ± 15.3% predicted). Each subject underwent resting spirometry (area under the maximal expiratory flow-volume curve - A(ex) was calculated). Subsequently, they performed maximal incremental cycle ergometer exercise for determination of V’O2max, Wmax.
Results: Significant correlation was found between A(ex) and V’O2max (r = 0.57, p < 0.001). In the group of severe COPD significant correlation was found between A(ex) and Wmax (r = 0.50 p < 0.05).
Conclusions: In chronic obstructive pulmonary disease, the index - area under the maximal expiratory flow-volume curve - A(ex), could be useful in assesment of COPD severity and in predicting exercise capacity.

Abstract

Introduction: Patients with chronic obstructive pulmonary disease (COPD) often present reduced exercise tolerance. Limitation of exercise capacity in COPD is an essential feature, which can be accurately determined by incremental cycle ergometry. The relationship between resting lung function variables and exercise capacity has been studied extensively in COPD patients. A clear relationship between resting pulmonary function testing and exercise capacity has not been established. The present study was designed to assess the accuracy of new index such as area under the maximal expiratory flow-volume curve [A(ex)] in predicting exercise capacity (expressed by maximum oxygen uptake - V’O2max and maximal mechanical work - Wmax) in COPD patients.
Material and methods: The study was performed on 41 patients with mild - to severe COPD (FEV1, 57.2 ± 15.3% predicted). Each subject underwent resting spirometry (area under the maximal expiratory flow-volume curve - A(ex) was calculated). Subsequently, they performed maximal incremental cycle ergometer exercise for determination of V’O2max, Wmax.
Results: Significant correlation was found between A(ex) and V’O2max (r = 0.57, p < 0.001). In the group of severe COPD significant correlation was found between A(ex) and Wmax (r = 0.50 p < 0.05).
Conclusions: In chronic obstructive pulmonary disease, the index - area under the maximal expiratory flow-volume curve - A(ex), could be useful in assesment of COPD severity and in predicting exercise capacity.
Citation Formats

Keywords

cardiopulmonary exercise testing; chronic obstructive pulmonary disease; maximum oxygen uptake; exercise capacity

About this article
Title

Prediction of exercise capacity in chronic obstructive pulmonary disease patients on the basis of maximum expiratory flow-volume curve

Journal

Advances in Respiratory Medicine

Issue

Vol 75, No 3 (2007)

Pages

213-218

Published online

2007-07-30

Bibliographic record

Pneumonol Alergol Pol 2007;75(3):213-218.

Keywords

cardiopulmonary exercise testing
chronic obstructive pulmonary disease
maximum oxygen uptake
exercise capacity

Authors

Marzena Trzaska-Sobczak
Władysław Pierzchała

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