open access

Vol 76, No 2 (2008)
ORIGINAL PAPERS
Published online: 2008-04-28
Submitted: 2013-02-22
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The coexistence of the impaired exercise tolerance in patients with obstructive sleep apnea with gastroesophageal reflux

Iwona Hawryłkiewicz, Dariusz Dziedzic, Robert Pływaczewski, Dorota Górecka
Pneumonol Alergol Pol 2008;76(2):83-87.

open access

Vol 76, No 2 (2008)
ORIGINAL PAPERS
Published online: 2008-04-28
Submitted: 2013-02-22

Abstract


Introduction: Gastroesophageal reflux (GERD) is a frequent disease in patients with obstructive sleep apnea (OSA). The aim of the study was to evaluate possible correlation between the impairement of exercise tolerance and GERD.
Material and methods: We examined 18 patients with OSA, mean AHI - 44 ± 22; 6 females, 12 males, mean age 55 ± 9 years. All patients were treated for metabolic disorders and for hypertension or coronary artery disease. In all patients gastroscopy was performed with 24h pHmetry and 6MWT.
Results: In 12 patients GERD was found, in 14 patients esophagitis was diagnosed (among them there were 3 patients without GERD). Patients with GERD were younger (53 ± 7 vs. 59 ± 11 years) and more obese (BMI - 38 ± 5 vs. 36 ± 9 kg/m2). During 6MWT the distance covered was shorter (in % of normal values) in GERD subjects: 78 ± 17 vs. 86 ± 22%) and desaturation was deeper (91 ± 3 vs. 94 ± 3%).
Conclusions: Despite some tendencies the relationship between GERD and impairement of exercise tolerance in OSA patients was not statistically significant. Perhaps study in larger group of subjects will be more reliable.

Abstract


Introduction: Gastroesophageal reflux (GERD) is a frequent disease in patients with obstructive sleep apnea (OSA). The aim of the study was to evaluate possible correlation between the impairement of exercise tolerance and GERD.
Material and methods: We examined 18 patients with OSA, mean AHI - 44 ± 22; 6 females, 12 males, mean age 55 ± 9 years. All patients were treated for metabolic disorders and for hypertension or coronary artery disease. In all patients gastroscopy was performed with 24h pHmetry and 6MWT.
Results: In 12 patients GERD was found, in 14 patients esophagitis was diagnosed (among them there were 3 patients without GERD). Patients with GERD were younger (53 ± 7 vs. 59 ± 11 years) and more obese (BMI - 38 ± 5 vs. 36 ± 9 kg/m2). During 6MWT the distance covered was shorter (in % of normal values) in GERD subjects: 78 ± 17 vs. 86 ± 22%) and desaturation was deeper (91 ± 3 vs. 94 ± 3%).
Conclusions: Despite some tendencies the relationship between GERD and impairement of exercise tolerance in OSA patients was not statistically significant. Perhaps study in larger group of subjects will be more reliable.
Get Citation

Keywords

exercise tolerance; OSA; gastroesophageal reflux

About this article
Title

The coexistence of the impaired exercise tolerance in patients with obstructive sleep apnea with gastroesophageal reflux

Journal

Advances in Respiratory Medicine

Issue

Vol 76, No 2 (2008)

Pages

83-87

Published online

2008-04-28

Bibliographic record

Pneumonol Alergol Pol 2008;76(2):83-87.

Keywords

exercise tolerance
OSA
gastroesophageal reflux

Authors

Iwona Hawryłkiewicz
Dariusz Dziedzic
Robert Pływaczewski
Dorota Górecka

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