Multimedialna platforma wiedzy medycznej Internetowa Księgarnia Medyczna Kalendarium Konferencji
Advances in Respiratory Medicine
MENU
Shortcuts Submit an article Author Guidelines Ahead Of Print Author statement Editorial Policy and Information for Authors Reviewers 2018

open access

Vol 77, No 1 (2009)
CASE REPORTS
Published online: 2008-12-19
Submitted: 2013-02-22
View PDF Download PDF file
Get Citation

Common variable immunodeficiency in a patient with suspected sarcoidosis

Katarzyna Modrzewska, Elżbieta Wiatr, Renata Langfort, Karina Oniszh, Kazimierz Roszkowski-Śliż
Pneumonol Alergol Pol 2009;77(1):91-97.

open access

Vol 77, No 1 (2009)
CASE REPORTS
Published online: 2008-12-19
Submitted: 2013-02-22

Abstract

Common variable immunodeficiency is a primary immunodeficiency disease, characterized by hypogammaglobulinemia, low serum immunoglobulin concentrations, and recurrent bacterial infections of the respiratory and gastrointestinal tracts. We report on a 33-year-old patient with suspected sarcoidosis, diagnosed on the basis of an open lung biopsy, who was admitted to the National Tuberculosis and Lung Diseases Research Institute because of severe pneumonia and streptococcal sepsis. During diagnostics based on typical, clinical and laboratory features, CVID was diagnosed. The antibiotic treatment was successfully administered and the patient was directed to supplementary treatment.

Abstract

Common variable immunodeficiency is a primary immunodeficiency disease, characterized by hypogammaglobulinemia, low serum immunoglobulin concentrations, and recurrent bacterial infections of the respiratory and gastrointestinal tracts. We report on a 33-year-old patient with suspected sarcoidosis, diagnosed on the basis of an open lung biopsy, who was admitted to the National Tuberculosis and Lung Diseases Research Institute because of severe pneumonia and streptococcal sepsis. During diagnostics based on typical, clinical and laboratory features, CVID was diagnosed. The antibiotic treatment was successfully administered and the patient was directed to supplementary treatment.

Full Text:

View PDF Download PDF file
Get Citation

Keywords

common variable immunodeficiency; granulomatous disease; hypogammaglobulinemia; pneumonia

About this article
Title

Common variable immunodeficiency in a patient with suspected sarcoidosis

Journal

Advances in Respiratory Medicine

Issue

Vol 77, No 1 (2009)

Pages

91-97

Published online

2008-12-19

Bibliographic record

Pneumonol Alergol Pol 2009;77(1):91-97.

Keywords

common variable immunodeficiency
granulomatous disease
hypogammaglobulinemia
pneumonia

Authors

Katarzyna Modrzewska
Elżbieta Wiatr
Renata Langfort
Karina Oniszh
Kazimierz Roszkowski-Śliż

References (14)
  1. Thickett KM, Kumararatne DS, Banerjee AK, et al. Common variable immune deficiency: respiratory manifestations, pulmonary function and high-resolution CT scan findings. QJM. 2002; 95(10): 655–662.
    PubMed
  2. Geha R, Notarangelo L, Casanova JL, et al. Primary immunodeficiency diseases: An update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. Journal of Allergy and Clinical Immunology. 2007; 120(4): 776–794.
    CrossRef
  3. Kuś J, Maziarka D. Common variable immunodeficiency — clinical aspect and results of treatment. Pneumonol Alergol Pol. 1997; 65: 187–197.
  4. Bayry J, Hermine O, Webster DA, et al. Common variable immunodeficiency: the immune system in chaos. Trends Mol Med. 2005; 11(8): 370–376.
    CrossRefPubMed
  5. Mechanic LJ, Dikman S, Cunningham-Rundles C. Granulomatous disease in common variable immunodeficiency. Ann Intern Med. 1997; 127(8 Pt 1): 613–617.
    PubMed
  6. Kainulainen L, Varpula M, Liippo K, et al. Pulmonary abnormalities in patients with primary hypogammaglobulinemia. J Allergy Clin Immunol. 1999; 104(5): 1031–1036.
    PubMed
  7. Kuś J, Maziarka D. Common variable immunodeficiency in an adult respiratory clinic. Immunol Pol. 1993; 18: 329–333.
  8. Park JES, Beal I, Dilworth JP, et al. The HRCT appearances of granulomatous pulmonary disease in common variable immune deficiency. Eur J Radiol. 2005; 54(3): 359–364.
    CrossRefPubMed
  9. Orange JS, Hossny EM, Weiler CR, et al. Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology. Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology. J Allergy Clin Immunol. 2006; 117(4 Suppl): S525–S553.
    CrossRefPubMed
  10. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol. 1999; 92(1): 34–48.
    CrossRefPubMed
  11. Moratto D, Gulino AV, Fontana S, et al. Combined decrease of defined B and T cell subsets in a group of common variable immunodeficiency patients. Clin Immunol. 2006; 121(2): 203–214.
    CrossRefPubMed
  12. Vitoratos N, Bakas P, Kalampani H, et al. Maternal common variable immunodeficiency and pregnancy. J Obstet Gynaecol. 1999; 19(6): 654–655.
    CrossRefPubMed
  13. Roifman CM, Schroeder H, Berger M, et al. Comparison of the efficacy of IGIV-C, 10% (caprylate/chromatography) and IGIV-SD, 10% as replacement therapy in primary immune deficiency. A randomized double-blind trial. Int Immunopharmacol. 2003; 3(9): 1325–1333.
    PubMed
  14. Shah KH, Levinson RD, Yu F, et al. Birdshot chorioretinopathy. Surv Ophthalmol. 2005; 50(6): 519–541.
    CrossRefPubMed

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Czasopismo Pneumonologia i Alergologia Polska dostęne jest również w Ikamed - księgarnia medyczna

Wydawcą serwisu jest "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl