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Vol 77, No 6 (2009)
REVIEWS
Published online: 2009-11-30
Submitted: 2013-02-22
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Chlamydial infection in asthma. Macrolide treatment

Magdalena Kosińska, Maria Kraus-Filarska
Pneumonol Alergol Pol 2009;77(6):541-548.

open access

Vol 77, No 6 (2009)
REVIEWS
Published online: 2009-11-30
Submitted: 2013-02-22

Abstract

Atypical microorganism infections, including Chlamydophila pneumoniae, play an important role in asthma course. A significant influence of chlamydial infection on severity of asthma exacerbations and increase in chronic asthma symptoms has been shown. The group of medication with high antibacterial activity against atypical microorganisms are macrolides, which also have anti-inflammatory and immunomodulatory effects. Macrolide treatment in patients with asthma can be connected with additional therapeutic benefits. Mechanism of action of these antibiotics is not ultimately clarified and further studies are required.

Abstract

Atypical microorganism infections, including Chlamydophila pneumoniae, play an important role in asthma course. A significant influence of chlamydial infection on severity of asthma exacerbations and increase in chronic asthma symptoms has been shown. The group of medication with high antibacterial activity against atypical microorganisms are macrolides, which also have anti-inflammatory and immunomodulatory effects. Macrolide treatment in patients with asthma can be connected with additional therapeutic benefits. Mechanism of action of these antibiotics is not ultimately clarified and further studies are required.
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Keywords

asthma; Chlamydophila pneumoniae; macrolides

About this article
Title

Chlamydial infection in asthma. Macrolide treatment

Journal

Advances in Respiratory Medicine

Issue

Vol 77, No 6 (2009)

Pages

541-548

Published online

2009-11-30

Bibliographic record

Pneumonol Alergol Pol 2009;77(6):541-548.

Keywords

asthma
Chlamydophila pneumoniae
macrolides

Authors

Magdalena Kosińska
Maria Kraus-Filarska

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