Multimedialna platforma wiedzy medycznej Internetowa Księgarnia Medyczna Kalendarium Konferencji
Advances in Respiratory Medicine
MENU
Shortcuts Submit an article Author Guidelines Ahead Of Print Author statement Editorial Policy and Information for Authors Reviewers 2018

open access

Vol 78, No 1 (2010)
REVIEWS
Published online: 2010-01-29
Submitted: 2013-02-22
View PDF (polish) Download PDF file
Get Citation

Microbiological diagnosis of respiratory infections caused by Legionella pneumophila

Natalia Rokosz, Waldemar Rastawicki, Aleksandra Anna Zasada, Milena Baczewska-Rej
Pneumonol Alergol Pol 2010;78(1):54-59.

open access

Vol 78, No 1 (2010)
REVIEWS
Published online: 2010-01-29
Submitted: 2013-02-22

Abstract

Legionella pneumophila is an important causative agent of pneumonia in humans which is difficult to diagnose because the signs and symptoms are nonspecific and do not distinguish Legionella infection from other common causes of pneumonia. Currently, the diagnosis of Legionnaires’ disease is based on phenotyping (culture, antibody detection in human sera, antigen detection in urine) and genotyping methods such as PCR (polymerase chain reaction). This review focuses on current diagnostic tests for surveillance of Legionella pneumophila infections in Poland.

Abstract

Legionella pneumophila is an important causative agent of pneumonia in humans which is difficult to diagnose because the signs and symptoms are nonspecific and do not distinguish Legionella infection from other common causes of pneumonia. Currently, the diagnosis of Legionnaires’ disease is based on phenotyping (culture, antibody detection in human sera, antigen detection in urine) and genotyping methods such as PCR (polymerase chain reaction). This review focuses on current diagnostic tests for surveillance of Legionella pneumophila infections in Poland.

Full Text:

View PDF (polish) Download PDF file
Get Citation

Keywords

Legionella pneumophila; Legionnaires’disease; legionellosis; laboratory evidence of Legionella infection; pulmonary infection

About this article
Title

Microbiological diagnosis of respiratory infections caused by Legionella pneumophila

Journal

Advances in Respiratory Medicine

Issue

Vol 78, No 1 (2010)

Pages

54-59

Published online

2010-01-29

Bibliographic record

Pneumonol Alergol Pol 2010;78(1):54-59.

Keywords

Legionella pneumophila
Legionnaires’disease
legionellosis
laboratory evidence of Legionella infection
pulmonary infection

Authors

Natalia Rokosz
Waldemar Rastawicki
Aleksandra Anna Zasada
Milena Baczewska-Rej

References (24)
  1. Bartram J, Yves Ch, Lee J, et al. Legionella and prevention of legionellosis. Publication of the World Health Organization. 2007.
  2. Jahnz-Różyk K, Targowski T, Jurkiewicz D, et al. Bakterie atypowe w zakażeniach dróg oddechowych — patogeneza i diagnostyka. Pol. Merk. Lek. 2008; 149(XXIV): 149, 412.
  3. Diederen BMW, de Jong CMA, Marmouk F, et al. Evaluation of real-time PCR for the early detection of Legionella pneumophila DNA in serum samples. J Med Microbiol. 2007; 56(Pt 1): 94–101.
    CrossRefPubMed
  4. Diederen BMW, Kluytmans JA, Peeters MF. Evaluation of Vircell enzyme-linked immunosorbent assay and indirect immunofluorescence assay for detection of antibodies against Legionella pneumophila. Clin Vaccine Immunol. 2006; 13(3): 361–364.
    CrossRefPubMed
  5. Dirven K, Ieven M, Peeters MF, et al. Comparison of three Legionella urinary antigen assays during an outbreak of legionellosis in Belgium. J Med Microbiol. 2005; 54(Pt 12): 1213–1216.
    CrossRefPubMed
  6. Molinos L. [Detection of antigens in urine]. Arch Bronconeumol. 2006; 42(3): 101–103.
    PubMed
  7. Fields BS, Benson RF, Besser RE. Legionella and Legionnaires' disease: 25 years of investigation. Clin Microbiol Rev. 2002; 15(3): 506–526.
    PubMed
  8. Jahnz-Różyk K, Targowski T. Zakażenia dróg oddechowych drobnoustrojami atypowymi a astma oskrzelowa. Pol. Merk. Lek. 2007; XXIII: 137, 325.
  9. Palusińska-Szych M, Cendrowska-Pinkosz M. Występowanie i chorobotwórczość bakterii z rodziny Legionellaceae. Postępy Hig Med Dośw. 2008; 62: 337–353.
  10. Kohler RB, Winn WC, Wheat LJ. Onset and duration of urinary antigen excretion in Legionnaires disease. J Clin Microbiol. 1984; 20(4): 605–607.
    PubMed
  11. Stypułkowska-Misiurewicz H. Legioneloza (choroba legionistów). In: Naruszewicz-Lesiuk D, Magdzik W. ed. Zakażenia i zarażenia człowieka. Wydawnictwo Lekarskie PZWL, Warszawa 2001.
  12. Kołodyński J, Jankowski S. Legionella pneumophila — epidemiologia i chorobotwórczość. Adv Clin Exp Med. 2004; 13: 645–649.
  13. Pancer K, Pawińska A, Rabczenko D, et al. Odpowiedź odpornościowa w klasie IgM na zakażenie Legionella pneumophila u dzieci. Przegl Epidemiol. 2007; 61: 401–407.
  14. Maiwald M, Helbig J, Luck P. Laboratory methods for the diagnosis of Legionella infections. J. Microbiol. Meth. 1998; 33: 59–79.
  15. Unit for Surveillance and Control of Communicable Diseases. Legionnaires disease in a neonatal unit of a private hospital, Cyprus, December 2008: preliminary outbreak report. Euro Surveill. 2009; 14(2).
    PubMed
  16. Stypułkowska-Misiurewicz H, Pancer K. Legioneloza — nowe zagrożenie w Polsce. Przegl Epidemiol. 2002; 56: 567–576.
  17. Stypułkowska-Misiurewicz H, Krogulska B, Pancer K, Matuszewska R. Metodyka wykrywania i oznaczania bakterii z rodzaju Legionella w środowisku wodnym i w materiale klinicznym. . Wyd. Met. PZH, Warszawa 2001: 1–47.
  18. Murdoch DR. Diagnosis of Legionella infection. Clin Infect Dis. 2003; 36(1): 64–69.
    CrossRefPubMed
  19. Pancer K, Rabczanko D, Krogulska B, et al. Mikrobiologiczna ocena zagrożenia legionelozą oraz zastosowanie metody eliminacji Legionella pneumophila z sieci wodnych budynków szpitalnych. Przegl Epidemiol. 2008; 62: 439–446.
  20. Stypułkowska-Misiurewicz H, Pancer K. Legioneloza w Polsce w latach 2001–2002 na tle sytuacji epidemiologicznej w Europie. Przegl Epidemiol. 2003; 57: 599–606.
  21. Pancer K, Stypułkowska-Misiurewicz H. Gorączka Pontiac — pozapłucna postać legionelozy. Przegl Epidemiol. 2003; 57: 607–612.
  22. Rojas A, Navarro MD, Fornés FE, et al. Value of serological testing for diagnosis of legionellosis in outbreak patients. J Clin Microbiol. 2005; 43(8): 4022–4025.
    CrossRefPubMed
  23. Wever PC, Yzerman EP, Kuijper EJ, et al. Rapid diagnosis of Legionnaires' disease using an immunochromatographic assay for Legionella pneumophila serogroup 1 antigen in urine during an outbreak in the Netherlands. J Clin Microbiol. 2000; 38(7): 2738–2739.
    PubMed
  24. Kondrusik M, Daniluk J, Siwak E, et al. [Infection with Legionella pneumophilia]. Pneumonol Alergol Pol. 1994; 62(1-2): 106–111.
    PubMed

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Czasopismo Pneumonologia i Alergologia Polska dostęne jest również w Ikamed - księgarnia medyczna

Wydawcą serwisu jest "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl