open access

Vol 79, No 3 (2011)
REVIEWS
Published online: 2011-04-21
Submitted: 2013-02-22

Balance of proteinases and antiproteinases and smoking tobacco

Joanna Kołodziejczyk, Milena Wojciechowska, Zbigniew Bartuzi, Andrzej Dziedziczko
Pneumonol Alergol Pol 2011;79(3):207-214.

open access

Vol 79, No 3 (2011)
REVIEWS
Published online: 2011-04-21
Submitted: 2013-02-22

Abstract

Smoking tobacco can induce formation of inflammable state in respiratory tract and cause lungs damage. Experimental investigations affirm, that the exposure to tobacco smoke causes growth of penetrability of blood-vessels, which favors the enlarged migration of inflammable cells. The growth of exposure to reactive forms of oxygen and concentration changes of cellular antioxidants enzymes, leads to disorders in balance of proteinases and antiproteinases and oxidative stress. As the years go, the disorders mentioned above can lead to deterioration of ventilating efficiency of lungs, and consequently to pronouncement chronic obstructive pulmonary disease (COPD), which becomes serious problem on a world scale.
Pneumonol. Alergol. Pol. 2011; 79, 3: 207-214

Keywords

smoking tobacco; elastase; alpha-1-antitrypsin; balance of proteinases and antiproteinases

About this article
Title

Balance of proteinases and antiproteinases and smoking tobacco

Journal

Advances in Respiratory Medicine

Issue

Vol 79, No 3 (2011)

Pages

207-214

Published online

2011-04-21

Bibliographic record

Pneumonol Alergol Pol 2011;79(3):207-214.

Keywords

smoking tobacco
elastase
alpha-1-antitrypsin
balance of proteinases and antiproteinases

Authors

Joanna Kołodziejczyk
Milena Wojciechowska
Zbigniew Bartuzi
Andrzej Dziedziczko

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