open access

Vol 79, No 4 (2011)
CASE REPORTS
Published online: 2011-06-15
Submitted: 2013-02-22
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Granuloma of epididymis of patient treated with intravesical BCG therapy — complication of BCG therapy or tuberculosis?

Dorota Michałowska-Mitczuk, Sylwia Brzezińska, Ewa Augustynowicz-Kopeć, Renata Langfort
Pneumonol Alergol Pol 2011;79(4):305-308.

open access

Vol 79, No 4 (2011)
CASE REPORTS
Published online: 2011-06-15
Submitted: 2013-02-22

Abstract

We present a case of 72-year old man treated from 2007 for superficial bladder carcinoma. Patient had undergone surgical intervention for transitional cell carcinoma of the bladder, followed by BCG therapy. Two years later enlarged right testis and epididymis was observed. A resection was carried out. Histologic examination revealed in epididymis cauda granulomatous infiltration with eosinophillic necrosis. No bacteriologic tests of resected material were performed. Suspecting BCG infection or TB patient was referred to the Instititute of Tuberculosis and Lung Diseases in Warsaw for pulmonary evaluation. Chest X-ray, chest CT scan and bronchoscopy were performed but beside revealing scars in bronchi suggesting a history of TB did not contribute to the diagnosis. Tuberculin skin test was 21 mm. Diagnosis was determinated by spoligotyping which found bacille of Mycobacterium tuberculosis in specimen preserved in paraffin block. Tuberculosis of right epididymis and past pulmonary tuberculosis was diagnosed. Patient was treated with rifampin, isoniazid and pirazynamid.
Pneumonol. Alergol. Pol. 2011; 79, 4: 305–308

Abstract

We present a case of 72-year old man treated from 2007 for superficial bladder carcinoma. Patient had undergone surgical intervention for transitional cell carcinoma of the bladder, followed by BCG therapy. Two years later enlarged right testis and epididymis was observed. A resection was carried out. Histologic examination revealed in epididymis cauda granulomatous infiltration with eosinophillic necrosis. No bacteriologic tests of resected material were performed. Suspecting BCG infection or TB patient was referred to the Instititute of Tuberculosis and Lung Diseases in Warsaw for pulmonary evaluation. Chest X-ray, chest CT scan and bronchoscopy were performed but beside revealing scars in bronchi suggesting a history of TB did not contribute to the diagnosis. Tuberculin skin test was 21 mm. Diagnosis was determinated by spoligotyping which found bacille of Mycobacterium tuberculosis in specimen preserved in paraffin block. Tuberculosis of right epididymis and past pulmonary tuberculosis was diagnosed. Patient was treated with rifampin, isoniazid and pirazynamid.
Pneumonol. Alergol. Pol. 2011; 79, 4: 305–308
Get Citation

Keywords

BCG infection; male genital tuberculosis; spoligotyping

About this article
Title

Granuloma of epididymis of patient treated with intravesical BCG therapy — complication of BCG therapy or tuberculosis?

Journal

Advances in Respiratory Medicine

Issue

Vol 79, No 4 (2011)

Pages

305-308

Published online

2011-06-15

Bibliographic record

Pneumonol Alergol Pol 2011;79(4):305-308.

Keywords

BCG infection
male genital tuberculosis
spoligotyping

Authors

Dorota Michałowska-Mitczuk
Sylwia Brzezińska
Ewa Augustynowicz-Kopeć
Renata Langfort

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