open access

Vol 52, No 6 (2021)
Clinical vignette
Submitted: 2021-05-05
Accepted: 2021-06-17
Published online: 2021-11-08
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Diagnostic and treatment dilemmas in case of the severe course of multicentric Castleman disease

Michalina Tamowicz1, Agnieszka Piekarska2, Michał Kunc3, Magdalena Dutka2, Ewa Zarzycka2, Wojciech Biernat3, Maria Bieniaszewska2, Jan Maciej Zaucha4
DOI: 10.5603/AHP.2021.0100
·
Acta Haematol Pol 2021;52(6):601-603.
Affiliations
  1. Gdański Uniwersytet Medyczny
  2. Department of Hematology and Transplantology, Medical University of Gdansk, SMOLUCHOWSKIEGO 17 Gdańsk, 80-214 Gdansk, Poland
  3. Department of Pathomorfology, Medical University of Gdańsk, SMOLUCHOWSKIEGO 17 Gdańsk, 80-214 Gdansk, Poland
  4. Department of Hematology and Transplantology, Medical University of Gdansk, SMOLUCHOWSKIEGO 17 Gdańsk, 80-214 Gdansk, Poland

open access

Vol 52, No 6 (2021)
CLINICAL VIGNETTE
Submitted: 2021-05-05
Accepted: 2021-06-17
Published online: 2021-11-08

Abstract

Not available

Abstract

Not available
Get Citation

Keywords

multicentric Castleman disease, TAFRO

About this article
Title

Diagnostic and treatment dilemmas in case of the severe course of multicentric Castleman disease

Journal

Acta Haematologica Polonica

Issue

Vol 52, No 6 (2021)

Article type

Clinical vignette

Pages

601-603

Published online

2021-11-08

Page views

2944

Article views/downloads

173

DOI

10.5603/AHP.2021.0100

Bibliographic record

Acta Haematol Pol 2021;52(6):601-603.

Keywords

multicentric Castleman disease
TAFRO

Authors

Michalina Tamowicz
Agnieszka Piekarska
Michał Kunc
Magdalena Dutka
Ewa Zarzycka
Wojciech Biernat
Maria Bieniaszewska
Jan Maciej Zaucha

References (10)
  1. Castleman B, Iverson L, Menendez V. Localized mediastinal lymph-node hyperplasia resembling thymoma. Cancer. 1956; 9(4): 822–830, doi: 10.1002/1097-0142(195607/08)9:4<822::aid-cncr2820090430>3.0.co;2-4.
  2. Gaba AR, Stein RS, Sweet DL, et al. Multicentric giant lymph node hyperplasia. Am J Clin Pathol. 1978; 69(1): 86–90.
  3. Herrada J, Cabanillas F, Rice L, et al. The clinical behavior of localized and multicentric Castleman disease. Ann Intern Med. 1998; 128(8): 657–662.
  4. Fajgenbaum DC, Shilling D. Castleman disease pathogenesis. Hematol Oncol Clin North Am. 2018; 32(1): 11–21.
  5. Fajgenbaum DC, van Rhee F, Nabel CS. HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy. Blood. 2014; 123(19): 2924–2933.
  6. Kojima M, Motoori T, Asano S, et al. Histological diversity of reactive and atypical proliferative lymph node lesions in systemic lupus erythematosus patients. Pathol Res Pract. 2007; 203(6): 423–431.
  7. Kojima M, Motoori T, Nakamura S. Benign, atypical and malignant lymphoproliferative disorders in rheumatoid arthritis patients. Biomed Pharmacother. 2006; 60(10): 663–672.
  8. Fajgenbaum DC, Uldrick T, Bagg A, et al. International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease. Blood. 2017; 129(12): 1646–1657.
  9. Kawabata H, Takai K, Kojima M, et al. Castleman-Kojima disease (TAFRO syndrome): a novel systemic inflammatory disease characterized by a constellation of symptoms, namely, thrombocytopenia, ascites (anasarca), microcytic anemia, myelofibrosis, renal dysfunction, and organomegaly : a status report and summary of Fukushima (6 June, 2012) and Nagoya meetings (22 September, 2012). J Clin Exp Hematop. 2013; 53(1): 57–61.
  10. Wang HW, Pittaluga S, Jaffe ES. Multicentric Castleman disease: where are we now? . Semin Diagn Pathol. 2016; 33(5): 294–306.

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