English Polski
Vol 26, No 3 (2020)
Research paper
Published online: 2021-01-07

open access

Page views 616
Article views/downloads 1425
Get Citation

Connect on Social Media

Connect on Social Media

Fibrin sealant injection through the drain with adjuvant compression as a treatment of groin lymphatic complications after vascular operation

Tadeusz Grochowiecki1, Michał Macech1, Tomasz Jakimowicz1, Maciej Jędrasik1, Sławomir Nazarewski1
Acta Angiologica 2020;26(3):85-89.

Abstract

Introduction: Groin lymphatic complications after femoral artery operations are rare, but if developed, they
could be a source of severe complications that could be potentially fatal. The novel technique of combining
compression and application of Tisseel sealant (Baxter AG, Vienna, Austria) to treat lymphatic fistulas in the
groin region after common femoral artery exposure was evaluated.

Material and methods: Twelve groins from eleven patients with groin lymphatic complications were enrolled
into the study. Patients had femoral artery exposure during one of the following procedures: endovascular aortic
aneurysm repair, thrombendarterectomy or extra-anatomic by-pass. Postoperatively, average lymphatic drainage
through the drain was 140 ± 60 (range 48–300) mL per day. Intervention was performed at a median
of 12 (9–23) days after operation. The drain was cut off close to the skin, a thin double-channel catheter was
introduced as deep as possible through the drain and sealant was injected into the wound. Simultaneously,
the remaining part of the drain was removed, the orifice in the skin was sutured and a compression dressing
was kept in place for 24 hours. The median patient observation period was 13 months (range 2.5–23) and
surveillance of the groin was performed using ultrasonography.

Results: Early outcomes showed full technical success. None of the patients were readmitted due to lymphorrhea,
infection or poor wound healing during follow-up. No lymphoceles were detected by ultrasonography.

Conclusion: Fibrin glue injection augmented by compression is an effective method for treating postoperative
lymphatic fistulas and to prevent lymphorrhagia and lymphocele formation in the groin region after femoral
artery exposure.

Article available in PDF format

View PDF Download PDF file

References

  1. Tyndall S, Shepard A, Wilczewski J, et al. Groin lymphatic complications after arterial reconstruction. Journal of Vascular Surgery. 1994; 19(5): 858–864.
  2. Uhl C, Götzke H, Woronowicz S, et al. Treatment of Lymphatic Complications after Common Femoral Artery Endarterectomy. Ann Vasc Surg. 2020; 62: 382–386.
  3. Ploeg AJ, Lardenoye JWP, Peeters MPF, et al. Wound complications at the groin after peripheral arterial surgery sparing the lymphatic tissue: a double-blind randomized clinical trial. Am J Surg. 2009; 197(6): 747–751.
  4. Teixeira G, Loureiro L, Machado R, et al. Groin wound infection in vascular surgery. A one year institutional incidence. Angiologia e Cirurgia Vascular. 2015; 11(1): 3–10.
  5. Obara A, Dziekiewicz MA, Maruszynski M, et al. Lymphatic complications after vascular interventions. Wideochir Inne Tech Maloinwazyjne. 2014; 9(3): 420–426.
  6. Caiati JM, Kaplan D, Gitlitz D, et al. The value of the oblique groin incision for femoral artery access during endovascular procedures. Ann Vasc Surg. 2000; 14(3): 248–253.
  7. Swinnen J, Chao A, Tiwari A, et al. Vertical or transverse incisions for access to the femoral artery: a randomized control study. Ann Vasc Surg. 2010; 24(3): 336–341.
  8. Giovannacci L, Eugster Th, Stierli P, et al. Does fibrin glue reduce complications after femoral artery surgery? A randomised trial. Eur J Vasc Endovasc Surg. 2002; 24(3): 196–201.
  9. https://youtu.be/daPHIkGZCfE.
  10. https://www fda gov/media.
  11. Dietl B, Pfister K, Aufschläger C, et al. [Radiotherapy of inguinal lymphorrhea after vascular surgery. A retrospective analysis]. Strahlenther Onkol. 2005; 181(6): 396–400.
  12. Van den Brande P, von Kemp K, Aerden D, et al. Treatment of lymphocutaneous fistulas after vascular procedures of the lower limb: accurate wound reclosure and 3 weeks of consistent and continuing drainage. Ann Vasc Surg. 2012; 26(6): 833–838.
  13. Shermak MA, Yee K, Wong L, et al. Surgical management of groin lymphatic complications after arterial bypass surgery. Plast Reconstr Surg. 2005; 115(7): 1954–1962.
  14. Hamed O, Muck PE, Smith JM, et al. Use of vacuum-assisted closure (VAC) therapy in treating lymphatic complications after vascular procedures: new approach for lymphoceles. J Vasc Surg. 2008; 48(6): 1520–1523.
  15. Giberson W, McCarthy P, Kaufman B. Fibrin glue for the treatment of persistent lymphatic drainage. Journal of Pediatric Surgery. 1988; 23(12): 1188–1189.
  16. Boaventura P, Sobreira M, Yoshida W, et al. Tratamento de linfocele inguinal pós-operatória com injeção de cola de fibrina: relato de caso. Jornal Vascular Brasileiro. 2007; 6(2): 190–192.
  17. Silas AM, Forauer AR, Perrich KD, et al. Sclerosis of postoperative lymphoceles: avoidance of prolonged catheter drainage with use of a fibrin sealant. J Vasc Interv Radiol. 2006; 17(11 Pt 1): 1791–1795.
  18. Brinkhous KM, Walker SA. Prothrombin and fibrinogen in lymph. Am J Physiology. 1941; 132(3): 666–669.
  19. Blomstrand R, Nilsson IM, Dahlbäck O. Coagulation studies on human thoracic duct lymph. Scand J Clin Lab Invest. 1963; 15: 248–254.
  20. Mayanskii DN, Minnibaev MM. A comparative study of the clotting power of the blood and lymph. Bulletin of Experimental Biology and Medicine. 1966; 62(4): 1097–1098.
  21. Kuznik BI, Levin YM. Lymph coagulation and fibrinolytic activity. Gematologiya i transfuziologiya. 2012; 57: 42–47.
  22. Fantl P, Nelson JF. Coagulation in lymph. J Physiol. 1953; 122(1): 33–37.
  23. Müller N, Danckworth HP, Müller N, et al. [Coagulation properties of the extravascular fluid. I. Coagulation factors in thoracic-duct lymph]. Z Lymphol. 1980; 4(1): 11–17.