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Vol 26, No 2 (2020)
Case report
Published online: 2020-07-29

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Type I cryoglobulinemia related to Sjögren’s syndrome and MGUS: a case report

Kamil Klimas1, Rafał Małecki1
Acta Angiologica 2020;26(2):81-84.


Cryoglobulinemia is a rare disease caused by the specific antibodies which precipitate at low temperatures
being present within the blood serum. It is observed in the course of disorders such as autoimmune diseases,
lymphoproliferative neoplasms, and infectious diseases — mainly HCV infections. Three types of cryoglobulinemia
have been identified, differing in the type of immunoglobulins involved and symptoms being manifested. We are
presenting a case of a 61-year-old female patient with type I cryoglobulinemia related to Sjögren’s syndrome
and complicated by monoclonal gammopathy of undetermined significance.

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