open access

Vol 21, No 4 (2015)
Original papers
Published online: 2016-06-23

Risk factors for major leg amputation in patients treated endovascularly due to critical limb ischaemia

Agnieszka Hamera, Andrzej Olech, Klaudia Koza, Pawel Grzelazka, Adrianna Trofimiuk, Wioletta Banas, Karol Suppan, Jacek Budzynski
DOI: 10.5603/AA.2015.0025
·
Acta Angiologica 2015;21(4):122-128.

open access

Vol 21, No 4 (2015)
Original papers
Published online: 2016-06-23

Abstract

Introduction. Critical limb ischaemia (CLI) is an advanced phase of chronic lower extremity ischaemia linked to increased mortality, decreased quality of life, and the risk of leg amputation. The aim of this study was to determine factors affecting the risk of leg amputation among patients with CLI treated endovascularly as a first approach.

Material and methods. Of 118 patients treated endovascularly, 32 (27%) had a leg amputated. Their clinical data were analysed retrospectively.

Results. Patients who had a leg amputated initially had a higher Rutherford class, were older, and had a greater prevalence of comorbidities. In multivariate analysis, amputation-free survival was shortened by a history of dyslipidaemia, female gender, blood creatinine concentration, the need for target lesion revascularization, smoking habit, Rutherford class, and leukocyte blood count. Whereas, the factors which decreased the risk of leg amputation were: use of statins, the number of previous interventions, and blood LDL cholesterol concentration. Angiographic classification of lesion severity did not affect endovascular procedure outcome.

Conclusions. The risk of major amputation following endovascular treatment in patients with CLI was associated with a number of characteristics, mainly: atherosclerosis risk factors and necrosis advancement, and the number of reinterventions. To avoid endangering patients and the unnecessary utilization of resources, it would seem to be worth performing large studies to determine a risk stratification scoring system for patients with CLI, which could enable the qualification of risk-adjusted patients for endovascular or surgical revascularization or for primary leg amputation.

Keywords

critical limb ischaemia, endovascular treatment, outcome, lower limb amputation risk factors

About this article
Title

Risk factors for major leg amputation in patients treated endovascularly due to critical limb ischaemia

Journal

Acta Angiologica

Issue

Vol 21, No 4 (2015)

Pages

122-128

Published online

2016-06-23

DOI

10.5603/AA.2015.0025

Bibliographic record

Acta Angiologica 2015;21(4):122-128.

Keywords

critical limb ischaemia
endovascular treatment
outcome
lower limb amputation risk factors

Authors

Agnieszka Hamera
Andrzej Olech
Klaudia Koza
Pawel Grzelazka
Adrianna Trofimiuk
Wioletta Banas
Karol Suppan
Jacek Budzynski

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl