open access

Vol 21, No 3 (2015)
Original papers
Published online: 2016-03-01

Evaluation of blood prothrombotic parameters under the influence of physical activity

Zanna Fiodorenko-Dumas, Maciej Rabczynski, Rafal Malecki, Ilias Dumas, Malgorzata Paprocka-Borowicz, Malgorzata Gacka, Rajmund Adamiec
DOI: 10.5603/AA.2015.0016
Acta Angiologica 2015;21(3):93-98.

open access

Vol 21, No 3 (2015)
Original papers
Published online: 2016-03-01


Introduction. Blood is a suspension of cellular components in plasma. Its viscosity is affected by haematocrit, the aggregation ability of erythrocytes and the viscosity of plasma, conditioned by high-molecular fibrinogen proteins or lipoprotein. The increase of blood viscosity occurs in the course of many diseases leading to the formation of atherosclerotic lesions.

Material and methods. The study involved 50 patients with femoral-popliteal type of occlusion in stage IIB according to Fontaine’s classification. Before the training, the patients underwent a treadmill test evaluating claudication distance. The proposed training included physical exercise performed 3 times a week and lasting 30 minutes for a period of 6 months. Before and after the training, venous blood samples for laboratory tests were taken to determine the values of haematocrit, haemoglobin, as well as phosphatase and calcium D-dimers. The purpose of the study was to evaluate the impact of training on selected blood rheological parameters. In addition, the change in BMI values and the length of distance of relative claudication were evaluated in the prospect of changes in laboratory values.

Results. The applied training contributed to the reduction of selected blood parameters. Statistical significance was observed at p < 0.0001 for D-dimers, haematocrit and phosphatase. The changes in BMI values were reflected in the results of D-dimers and phosphatase. A statistical significance also occurred in the case of the extension of claudication distance and changes in the values of D-dimers, haematocrit and phosphatase.

Conclusions. The supervised training had an impact on the reduction of prothrombotic blood parameters. Health-oriented physical exercise can contribute to body weight decrease and painless distance extension.


blood, D-dimers, training, body weight

About this article

Evaluation of blood prothrombotic parameters under the influence of physical activity


Acta Angiologica


Vol 21, No 3 (2015)



Published online




Bibliographic record

Acta Angiologica 2015;21(3):93-98.


body weight


Zanna Fiodorenko-Dumas
Maciej Rabczynski
Rafal Malecki
Ilias Dumas
Malgorzata Paprocka-Borowicz
Malgorzata Gacka
Rajmund Adamiec

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